F2R, coagulation factor II thrombin receptor, 2149

N. diseases: 347; N. variants: 10
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2227831
rs2227831
Entrez Id: 2149
Gene Symbol: F2R
F2R
CUI: C0200665
Disease:
Platelet mean volume determination (procedure) 		G 0.800 GeneticVariation GWASDB New gene functions in megakaryopoiesis and platelet formation. 22139419 2011
dbSNP: rs2227831
rs2227831
Entrez Id: 2149
Gene Symbol: F2R
F2R
CUI: C0200665
Disease:
Platelet mean volume determination (procedure) 		G 0.800 GeneticVariation GWASCAT New gene functions in megakaryopoiesis and platelet formation. 22139419 2011
dbSNP: rs2227831
rs2227831
Entrez Id: 2149
Gene Symbol: F2R
F2R
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs2227827
rs2227827
Entrez Id: 2149
Gene Symbol: F2R
F2R
CUI: C3828530
Disease:
Platelet Component Distribution Width Measurement 		T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs2227777
rs2227777
Entrez Id: 2149
Gene Symbol: F2R
F2R
CUI: C0428474
Disease:
Serum LDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs2227777
rs2227777
Entrez Id: 2149
Gene Symbol: F2R
F2R
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs168753
rs168753
Entrez Id: 2149
Gene Symbol: F2R
F2R
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease 		0.010 GeneticVariation BEFREE In conclusion, we found that the PAR1 IVS-14 A/T rs168753 polymorphism was associated with the development of COPD. 26535635 2015
dbSNP: rs2227744
rs2227744
Entrez Id: 2149
Gene Symbol: F2R
F2R
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease 		0.010 GeneticVariation BEFREE Taken together, these data do not support a role for the rs2227744G>A F2R polymorphism in the development of COPD but suggest a protective role for this polymorphism from frequent exacerbations. 24973402 2014
dbSNP: rs11267092
rs11267092
Entrez Id: 2149
Gene Symbol: F2R
F2R
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.010 GeneticVariation BEFREE We evaluated the associations of the gene variations PAR-1 IVSn -14 A>T (rs168753), -506 Ins/Del (rs11267092) and -1426 C>T (rs32934) with renal cell carcinoma pathology and cancer specific survival. 23517743 2013
dbSNP: rs11267092
rs11267092
Entrez Id: 2149
Gene Symbol: F2R
F2R
CUI: C0006826
Disease:
Malignant Neoplasms 		0.010 GeneticVariation BEFREE We evaluated the associations of the gene variations PAR-1 IVSn -14 A>T (rs168753), -506 Ins/Del (rs11267092) and -1426 C>T (rs32934) with renal cell carcinoma pathology and cancer specific survival. 23517743 2013
dbSNP: rs168753
rs168753
Entrez Id: 2149
Gene Symbol: F2R
F2R
CUI: C0006826
Disease:
Malignant Neoplasms 		0.010 GeneticVariation BEFREE We evaluated the associations of the gene variations PAR-1 IVSn -14 A>T (rs168753), -506 Ins/Del (rs11267092) and -1426 C>T (rs32934) with renal cell carcinoma pathology and cancer specific survival. 23517743 2013
dbSNP: rs168753
rs168753
Entrez Id: 2149
Gene Symbol: F2R
F2R
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.010 GeneticVariation BEFREE We evaluated the associations of the gene variations PAR-1 IVSn -14 A>T (rs168753), -506 Ins/Del (rs11267092) and -1426 C>T (rs32934) with renal cell carcinoma pathology and cancer specific survival. 23517743 2013
dbSNP: rs32934
rs32934
Entrez Id: 2149
Gene Symbol: F2R
F2R
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.010 GeneticVariation BEFREE We evaluated the associations of the gene variations PAR-1 IVSn -14 A>T (rs168753), -506 Ins/Del (rs11267092) and -1426 C>T (rs32934) with renal cell carcinoma pathology and cancer specific survival. 23517743 2013
dbSNP: rs32934
rs32934
Entrez Id: 2149
Gene Symbol: F2R
F2R
CUI: C0006826
Disease:
Malignant Neoplasms 		0.010 GeneticVariation BEFREE We evaluated the associations of the gene variations PAR-1 IVSn -14 A>T (rs168753), -506 Ins/Del (rs11267092) and -1426 C>T (rs32934) with renal cell carcinoma pathology and cancer specific survival. 23517743 2013
dbSNP: rs780737633
rs780737633
Entrez Id: 2149
Gene Symbol: F2R
F2R
CUI: C0019337
Disease:
Heroin Dependence 		0.010 GeneticVariation BEFREE Here we examined potential association between heroin dependence and four single nucleotide polymorphisms (SNPs) of 5-HT receptors (A-1438G and T102C of HTR(2A), and G861C and A1180G of HTR(1B)) in a cohort of Han Chinese. 21839728 2011
dbSNP: rs778747981
rs778747981
Entrez Id: 2149
Gene Symbol: F2R
F2R
CUI: C0027051
Disease:
Myocardial Infarction 		0.010 GeneticVariation BEFREE These results indicated that G-33A polymorphism in TM might be a genetic risk factor for myocardial infarction. 12135317 2002
dbSNP: rs1235324522
rs1235324522
Entrez Id: 2149
Gene Symbol: F2R
F2R
CUI: C0948089
Disease:
Acute Coronary Syndrome 		0.010 GeneticVariation BEFREE The HPA-2 (Thr145 Met) and VNTR polymorphisms of the gene for GP Ibalpha have been studied previously in hospitalized patients with acute coronary syndromes. 11514372 2001