|
rs20455
|
KIF6;LOC107986594
|
Coronary heart disease
|
|
0.100 |
GeneticVariation |
BEFREE |
Our result suggests that KIF6 rs20455 polymorphism may not be associated with CHD susceptibility.
|
29304815 |
2018 |
|
rs20455
|
KIF6;LOC107986594
|
Coronary heart disease
|
|
0.100 |
GeneticVariation |
BEFREE |
Our findings indicate that the Trp719Arg polymorphism of the KIF6 gene is an important risk factor for developing MI and that allele 719Arg may have a protective association to present CHD in all populations.
|
28096762 |
2015 |
|
rs20455
|
KIF6;LOC107986594
|
Coronary heart disease
|
|
0.100 |
GeneticVariation |
BEFREE |
Trp 719Arg have an effect on development of Coronary Heart Disease but it is very useful for statin therapy.
|
26443250 |
2015 |
|
rs20455
|
KIF6;LOC107986594
|
Coronary heart disease
|
|
0.100 |
GeneticVariation |
BEFREE |
Meta-analyses of KIF6 Trp719Arg in coronary heart disease and statin therapeutic effect.
|
23236363 |
2012 |
|
rs20455
|
KIF6;LOC107986594
|
Coronary heart disease
|
|
0.100 |
GeneticVariation |
BEFREE |
Our data indicate that the assessment of KIF6 rs20455 and TAS2R50 rs1376251 genotypes are not useful for predicting statin induced cardiovascular risk reduction in men, but do predict CHD risk reduction in women in this elderly population.
|
22192511 |
2012 |
|
rs20455
|
KIF6;LOC107986594
|
Coronary heart disease
|
|
0.100 |
GeneticVariation |
BEFREE |
Survival bias and drug interaction can attenuate cross-sectional case-control comparisons of genes with health outcomes. An example of the kinesin-like protein 6 (KIF6) Trp719Arg polymorphism and coronary heart disease.
|
21435211 |
2011 |
|
rs20455
|
KIF6;LOC107986594
|
Coronary heart disease
|
|
0.100 |
GeneticVariation |
BEFREE |
Investigation of KIF6 Trp719Arg in a case-control study of coronary artery disease in Western Indians.
|
21810021 |
2011 |
|
rs20455
|
KIF6;LOC107986594
|
Coronary heart disease
|
|
0.100 |
GeneticVariation |
BEFREE |
A single nucleotide polymorphism (SNP) in KIF6, a member of the KIF9 family of kinesins, is associated with differential coronary event reduction from statin therapy in four randomized controlled trials; this SNP (rs20455) is also associated with the risk for coronary heart disease (CHD) in multiple prospective studies.
|
20886236 |
2011 |
|
rs20455
|
KIF6;LOC107986594
|
Coronary heart disease
|
|
0.100 |
GeneticVariation |
BEFREE |
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies.
|
20933357 |
2010 |
|
rs20455
|
KIF6;LOC107986594
|
Coronary heart disease
|
|
0.100 |
GeneticVariation |
BEFREE |
Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: the CARE and WOSCOPS trials.
|
18222353 |
2008 |
|
rs20455
|
KIF6;LOC107986594
|
Coronary heart disease
|
|
0.100 |
GeneticVariation |
BEFREE |
The 719Arg allele of KIF6 (rs20455) has been reported to be associated with increased risk of CHD in a large population-based prospective study, ARIC (Atherosclerosis Risk in Communities), and in the placebo arms of 2 statin trials, CARE (Cholesterol and Recurrent Events) and WOSCOPS (West of Scotland Coronary Prevention Study).
|
18222354 |
2008 |
|
rs20455
|
KIF6;LOC107986594
|
Coronary heart disease
|
|
0.100 |
GeneticVariation |
BEFREE |
We considered five variants that were associated with coronary heart disease in two studies and confirmed in the Atherosclerosis Risk in Communities study: rs20455 (KIF6), rs3900940 (MYH15), rs7439293 (PALLD), rs2298566 (SNX19), and rs1010 (VAMP8).
|
18073581 |
2007 |