Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7221274
rs7221274
Entrez Id: 22843
Gene Symbol: PPM1E
PPM1E
CUI: C1336708
Disease:
Testicular Germ Cell Tumor 		0.710 GeneticVariation BEFREE In the combined analysis, risk of TGCT was significantly associated with markers at four previously unreported loci: 4q22.2 in HPGDS (per-allele odds ratio (OR) = 1.19, 95% confidence interval (CI) = 1.12-1.26; P = 1.11 × 10(-8)), 7p22.3 in MAD1L1 (OR = 1.21, 95% CI = 1.14-1.29; P = 5.59 × 10(-9)), 16q22.3 in RFWD3 (OR = 1.26, 95% CI = 1.18-1.34; P = 5.15 × 10(-12)) and 17q22 (rs9905704: OR = 1.27, 95% CI = 1.18-1.33; P = 4.32 × 10(-13) and rs7221274: OR = 1.20, 95% CI = 1.12-1.28; P = 4.04 × 10(-9)), a locus that includes TEX14, RAD51C and PPM1E. 23666239 2013
dbSNP: rs7221274
rs7221274
Entrez Id: 22843
Gene Symbol: PPM1E
PPM1E
CUI: C1336708
Disease:
Testicular Germ Cell Tumor 		A 0.710 GeneticVariation GWASDB In the combined analysis, risk of TGCT was significantly associated with markers at four previously unreported loci: 4q22.2 in HPGDS (per-allele odds ratio (OR) = 1.19, 95% confidence interval (CI) = 1.12-1.26; P = 1.11 × 10(-8)), 7p22.3 in MAD1L1 (OR = 1.21, 95% CI = 1.14-1.29; P = 5.59 × 10(-9)), 16q22.3 in RFWD3 (OR = 1.26, 95% CI = 1.18-1.34; P = 5.15 × 10(-12)) and 17q22 (rs9905704: OR = 1.27, 95% CI = 1.18-1.33; P = 4.32 × 10(-13) and rs7221274: OR = 1.20, 95% CI = 1.12-1.28; P = 4.04 × 10(-9)), a locus that includes TEX14, RAD51C and PPM1E. 23666239 2013
dbSNP: rs9911578
rs9911578
Entrez Id: 22843
Gene Symbol: PPM1E
PPM1E
CUI: C0021704
Disease:
Intelligence 		T 0.700 GeneticVariation GWASCAT A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence. 29326435 2019
dbSNP: rs34430710
rs34430710
Entrez Id: 22843
Gene Symbol: PPM1E
PPM1E
CUI: C0871470
Disease:
Systolic Pressure 		A 0.700 GeneticVariation GWASCAT Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. 30224653 2018
dbSNP: rs66954617
rs66954617
Entrez Id: 22843
Gene Symbol: PPM1E
PPM1E
CUI: C0021704
Disease:
Intelligence 		A 0.700 GeneticVariation GWASCAT Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. 29942086 2018
dbSNP: rs138387343
rs138387343
Entrez Id: 4591;22843
Gene Symbol: TRIM37;PPM1E
TRIM37;PPM1E
CUI: C3548479
Disease:
response to bronchodilator 		C 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs146255527
rs146255527
Entrez Id: 22843
Gene Symbol: PPM1E
PPM1E
CUI: C3548479
Disease:
response to bronchodilator 		T 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs9911753
rs9911753
Entrez Id: 22843
Gene Symbol: PPM1E
PPM1E
CUI: C2698399
Disease:
Myeloperoxidase Measurement 		G 0.700 GeneticVariation GWASDB Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia. 23620142 2013