Disease: Inflammatory Bowel Diseases ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2043211
rs2043211
Entrez Id: 22900
Gene Symbol: CARD8
CARD8
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		0.030 GeneticVariation BEFREE There was no significant association between rs2043211 polymorphism and IBD, CD, and IC in overall population. 25564880 2015
dbSNP: rs2043211
rs2043211
Entrez Id: 22900
Gene Symbol: CARD8
CARD8
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		0.030 GeneticVariation BEFREE To understand the genetic association between CARD8/NALP3 and IBD in Koreans, we investigated seven CARD8, four NALP3 and four NOD2 SNPs in 650 Crohn's disease (CD), 660 ulcerative colitis (UC) patients and 688 controls from the Korean population. rs2043211 of CARD8 showed significant association with UC (P = 0.011; odds ratio = 1.50, 95% confidence intervals = 1.12-2.00, P = 0.006 under recessive model). 21248762 2011
dbSNP: rs2043211
rs2043211
Entrez Id: 22900
Gene Symbol: CARD8
CARD8
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		0.030 GeneticVariation BEFREE However, studies testing for the association of the CARD8 loss-of-function single-nucleotide polymorphism (SNP) rs2043211 with IBD have yielded mixed results. 20182451 2010