ATF6, activating transcription factor 6, 22926

N. diseases: 179; N. variants: 30
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2070150
rs2070150
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C2239176
Disease:
Liver carcinoma 		0.020 GeneticVariation BEFREE With TaqMan real-time PCR, the results showed that no significant association between XRCC4 (rs1805377) and ATF6 (rs2070150) and risk of HCC in the Thai population. 26925648 2016
dbSNP: rs2070150
rs2070150
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C2239176
Disease:
Liver carcinoma 		0.020 GeneticVariation BEFREE We identified a missense SNP (rs2070150) was significantly associated with susceptibility to HCC (p = 0.008, 0.001 and 0.007 in Beijing_302, Beijing_You'an and Guangxi samples, respectively). 24302549 2014
dbSNP: rs1042488900
rs1042488900
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011849
Disease:
Diabetes Mellitus 		0.010 GeneticVariation BEFREE No association with diabetes was showed in the meta-analyses of other six genetic variants, including SLC2A10 rs2335491, ATF6 rs2070150, KLF11 rs35927125, CASQ1 rs2275703, GNB3 C825T, and IL12B 1188A/C. 23922971 2013
dbSNP: rs1042488900
rs1042488900
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011847
Disease:
Diabetes 		0.010 GeneticVariation BEFREE No association with diabetes was showed in the meta-analyses of other six genetic variants, including SLC2A10 rs2335491, ATF6 rs2070150, KLF11 rs35927125, CASQ1 rs2275703, GNB3 C825T, and IL12B 1188A/C. 23922971 2013
dbSNP: rs1058405
rs1058405
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 GeneticVariation BEFREE Six SNPs showed nominal associations with type 2 diabetes (P = 0.001-0.04), including the nonsynonymous SNP rs1058405 (M67V) in exon 3 and rs11579627 in the 3' flanking region. 17327457 2007
dbSNP: rs1135983
rs1135983
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 GeneticVariation BEFREE Pro(145)Ala and Ser(157)Pro were in a complete linkage disequilibrium and showed a nominal association with type 2 diabetes (P = 0.05; odds ratio 2.3 [95% CI 1.0-5.2]) and with 30-min plasma insulin during oral glucose tolerance test in 287 nondiabetic individuals (P = 0.045). 16505252 2006
dbSNP: rs11579627
rs11579627
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 GeneticVariation BEFREE Six SNPs showed nominal associations with type 2 diabetes (P = 0.001-0.04), including the nonsynonymous SNP rs1058405 (M67V) in exon 3 and rs11579627 in the 3' flanking region. 17327457 2007
dbSNP: rs2070150
rs2070150
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0019163
Disease:
Hepatitis B 		0.010 GeneticVariation BEFREE Genetic Variations in XRCC4 (rs1805377) and ATF6 (rs2070150) are not Associated with Hepatocellular Carcinoma in Thai Patients with Hepatitis B Virus Infection. 26925648 2016
dbSNP: rs2070150
rs2070150
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0151517
Disease:
Complete atrioventricular block 		0.010 GeneticVariation BEFREE The present study was conducted to evaluate any association between SNP frequencies in two genes, XRCC4 (rs1805377) and ATF6 (rs2070150), and the risk of CHB and HCC development in Thai patients. 26925648 2016
dbSNP: rs2070150
rs2070150
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 GeneticVariation BEFREE Pro(145)Ala and Ser(157)Pro were in a complete linkage disequilibrium and showed a nominal association with type 2 diabetes (P = 0.05; odds ratio 2.3 [95% CI 1.0-5.2]) and with 30-min plasma insulin during oral glucose tolerance test in 287 nondiabetic individuals (P = 0.045). 16505252 2006
dbSNP: rs2070150
rs2070150
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011847
Disease:
Diabetes 		0.010 GeneticVariation BEFREE No association with diabetes was showed in the meta-analyses of other six genetic variants, including SLC2A10 rs2335491, ATF6 rs2070150, KLF11 rs35927125, CASQ1 rs2275703, GNB3 C825T, and IL12B 1188A/C. 23922971 2013
dbSNP: rs2070150
rs2070150
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011849
Disease:
Diabetes Mellitus 		0.010 GeneticVariation BEFREE No association with diabetes was showed in the meta-analyses of other six genetic variants, including SLC2A10 rs2335491, ATF6 rs2070150, KLF11 rs35927125, CASQ1 rs2275703, GNB3 C825T, and IL12B 1188A/C. 23922971 2013
dbSNP: rs761357250
rs761357250
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C4225297
Disease:
ACHROMATOPSIA 7 		T 0.800 CausalMutation CLINVAR Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia. 26029869 2015
dbSNP: rs1553227755
rs1553227755
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0152200
Disease:
Achromatopsia 		AG 0.700 CausalMutation CLINVAR
dbSNP: rs1558022158
rs1558022158
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C4225297
Disease:
ACHROMATOPSIA 7 		G 0.700 GeneticVariation CLINVAR
dbSNP: rs749537392
rs749537392
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0730292
Disease:
Macular dystrophy 		C 0.700 GeneticVariation CLINVAR
dbSNP: rs761129859
rs761129859
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C4225297
Disease:
ACHROMATOPSIA 7 		C 0.700 CausalMutation CLINVAR Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia. 26029869 2015
dbSNP: rs761129859
rs761129859
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0152200
Disease:
Achromatopsia 		C 0.700 CausalMutation CLINVAR Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia. 26029869 2015
dbSNP: rs761357250
rs761357250
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0152200
Disease:
Achromatopsia 		T 0.700 CausalMutation CLINVAR Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia. 26029869 2015
dbSNP: rs765383904
rs765383904
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0152200
Disease:
Achromatopsia 		CT 0.700 GeneticVariation CLINVAR
dbSNP: rs796065053
rs796065053
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0152200
Disease:
Achromatopsia 		A 0.700 CausalMutation CLINVAR Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia. 26029869 2015
dbSNP: rs796065053
rs796065053
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C4225297
Disease:
ACHROMATOPSIA 7 		A 0.700 CausalMutation CLINVAR Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia. 26029869 2015
dbSNP: rs797045170
rs797045170
Entrez Id: 22926;102724329
Gene Symbol: ATF6;LOC102724329
ATF6;LOC102724329
CUI: C4225297
Disease:
ACHROMATOPSIA 7 		T 0.700 CausalMutation CLINVAR Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia. 26029869 2015
dbSNP: rs797045170
rs797045170
Entrez Id: 22926;102724329
Gene Symbol: ATF6;LOC102724329
ATF6;LOC102724329
CUI: C0152200
Disease:
Achromatopsia 		T 0.700 CausalMutation CLINVAR Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia. 26029869 2015
dbSNP: rs797045171
rs797045171
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0152200
Disease:
Achromatopsia 		T 0.700 CausalMutation CLINVAR Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia. 26029869 2015