ATF6, activating transcription factor 6, 22926

N. diseases: 179; N. variants: 30
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1553227755
rs1553227755
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0152200
Disease:
Achromatopsia 		AG 0.700 CausalMutation CLINVAR
dbSNP: rs1558022158
rs1558022158
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C4225297
Disease:
ACHROMATOPSIA 7 		G 0.700 GeneticVariation CLINVAR
dbSNP: rs749537392
rs749537392
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0730292
Disease:
Macular dystrophy 		C 0.700 GeneticVariation CLINVAR
dbSNP: rs765383904
rs765383904
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0152200
Disease:
Achromatopsia 		CT 0.700 GeneticVariation CLINVAR
dbSNP: rs869320751
rs869320751
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C4225297
Disease:
ACHROMATOPSIA 7 		AG 0.700 CausalMutation CLINVAR
dbSNP: rs1135983
rs1135983
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 GeneticVariation BEFREE Pro(145)Ala and Ser(157)Pro were in a complete linkage disequilibrium and showed a nominal association with type 2 diabetes (P = 0.05; odds ratio 2.3 [95% CI 1.0-5.2]) and with 30-min plasma insulin during oral glucose tolerance test in 287 nondiabetic individuals (P = 0.045). 16505252 2006
dbSNP: rs2070150
rs2070150
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 GeneticVariation BEFREE Pro(145)Ala and Ser(157)Pro were in a complete linkage disequilibrium and showed a nominal association with type 2 diabetes (P = 0.05; odds ratio 2.3 [95% CI 1.0-5.2]) and with 30-min plasma insulin during oral glucose tolerance test in 287 nondiabetic individuals (P = 0.045). 16505252 2006
dbSNP: rs1058405
rs1058405
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 GeneticVariation BEFREE Six SNPs showed nominal associations with type 2 diabetes (P = 0.001-0.04), including the nonsynonymous SNP rs1058405 (M67V) in exon 3 and rs11579627 in the 3' flanking region. 17327457 2007
dbSNP: rs11579627
rs11579627
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 GeneticVariation BEFREE Six SNPs showed nominal associations with type 2 diabetes (P = 0.001-0.04), including the nonsynonymous SNP rs1058405 (M67V) in exon 3 and rs11579627 in the 3' flanking region. 17327457 2007
dbSNP: rs16849542
rs16849542
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0027404
Disease:
Narcolepsy 		0.700 GeneticVariation GWASDB Genome-wide association database developed in the Japanese Integrated Database Project. 19629137 2009
dbSNP: rs1006310
rs1006310
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0023508
Disease:
White Blood Cell Count procedure 		0.700 GeneticVariation GWASDB Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). 21738479 2011
dbSNP: rs10918137
rs10918137
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0023508
Disease:
White Blood Cell Count procedure 		0.700 GeneticVariation GWASDB Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). 21738479 2011
dbSNP: rs12124509
rs12124509
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0023508
Disease:
White Blood Cell Count procedure 		0.700 GeneticVariation GWASDB Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). 21738479 2011
dbSNP: rs2340721
rs2340721
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0023508
Disease:
White Blood Cell Count procedure 		0.700 GeneticVariation GWASDB Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). 21738479 2011
dbSNP: rs7519514
rs7519514
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0023508
Disease:
White Blood Cell Count procedure 		0.700 GeneticVariation GWASDB Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). 21738479 2011
dbSNP: rs905594
rs905594
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0023508
Disease:
White Blood Cell Count procedure 		0.700 GeneticVariation GWASDB Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). 21738479 2011
dbSNP: rs931778
rs931778
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0023508
Disease:
White Blood Cell Count procedure 		0.700 GeneticVariation GWASDB Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). 21738479 2011
dbSNP: rs1027700
rs1027700
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 GeneticVariation GWASDB Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 22158537 2011
dbSNP: rs11576878
rs11576878
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 GeneticVariation GWASDB Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 22158537 2011
dbSNP: rs11581556
rs11581556
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 GeneticVariation GWASDB Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 22158537 2011
dbSNP: rs4657121
rs4657121
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 GeneticVariation GWASDB Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 22158537 2011
dbSNP: rs1042488900
rs1042488900
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011849
Disease:
Diabetes Mellitus 		0.010 GeneticVariation BEFREE No association with diabetes was showed in the meta-analyses of other six genetic variants, including SLC2A10 rs2335491, ATF6 rs2070150, KLF11 rs35927125, CASQ1 rs2275703, GNB3 C825T, and IL12B 1188A/C. 23922971 2013
dbSNP: rs1042488900
rs1042488900
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011847
Disease:
Diabetes 		0.010 GeneticVariation BEFREE No association with diabetes was showed in the meta-analyses of other six genetic variants, including SLC2A10 rs2335491, ATF6 rs2070150, KLF11 rs35927125, CASQ1 rs2275703, GNB3 C825T, and IL12B 1188A/C. 23922971 2013
dbSNP: rs2070150
rs2070150
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011847
Disease:
Diabetes 		0.010 GeneticVariation BEFREE No association with diabetes was showed in the meta-analyses of other six genetic variants, including SLC2A10 rs2335491, ATF6 rs2070150, KLF11 rs35927125, CASQ1 rs2275703, GNB3 C825T, and IL12B 1188A/C. 23922971 2013
dbSNP: rs2070150
rs2070150
Entrez Id: 22926
Gene Symbol: ATF6
ATF6
CUI: C0011849
Disease:
Diabetes Mellitus 		0.010 GeneticVariation BEFREE No association with diabetes was showed in the meta-analyses of other six genetic variants, including SLC2A10 rs2335491, ATF6 rs2070150, KLF11 rs35927125, CASQ1 rs2275703, GNB3 C825T, and IL12B 1188A/C. 23922971 2013