DisGeNET - a database of gene-disease associations

PDXDC1, pyridoxal dependent decarboxylase domain containing 1, 23042

N. diseases: 24; N. variants: 26

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs3198697

Entrez Id:	23042
Gene Symbol:	PDXDC1

PDXDC1

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

A large electronic-health-record-based genome-wide study of serum lipids.

29507422

2018

dbSNP:

rs3198697

Entrez Id:	23042
Gene Symbol:	PDXDC1

PDXDC1

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASCAT

Discovery and refinement of loci associated with lipid levels.

24097068

2013

dbSNP:

rs3198697

Entrez Id:	23042
Gene Symbol:	PDXDC1

PDXDC1

CUI:	C0202236
Disease:

Triglycerides measurement

0.800

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

dbSNP:

rs11075253

Entrez Id:	23042;123803
Gene Symbol:	PDXDC1;NTAN1

PDXDC1;NTAN1

CUI:	C0523744
Disease:

Lipids measurement

0.800

GeneticVariation

GWASCAT

Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

22286219

2012

dbSNP:

rs11075253

Entrez Id:	23042;123803
Gene Symbol:	PDXDC1;NTAN1

PDXDC1;NTAN1

CUI:	C0523744
Disease:

Lipids measurement

0.800

GeneticVariation

GWASDB

Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

22286219

2012

dbSNP:

rs4500751

Entrez Id:	23042;123803
Gene Symbol:	PDXDC1;NTAN1

PDXDC1;NTAN1

CUI:	C0202177
Disease:

Phospholipid measurement

0.800

GeneticVariation

GWASCAT

Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.

22359512

2012

dbSNP:

rs4500751

Entrez Id:	23042;123803
Gene Symbol:	PDXDC1;NTAN1

PDXDC1;NTAN1

CUI:	C0202177
Disease:

Phospholipid measurement

0.800

GeneticVariation

GWASDB

Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.

22359512

2012

dbSNP:

rs1741

Entrez Id:	23042
Gene Symbol:	PDXDC1

PDXDC1

CUI:	C0005890
Disease:

Body Height

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs2966157

Entrez Id:	23042;54700
Gene Symbol:	PDXDC1;RRN3

PDXDC1;RRN3

CUI:	C0036341
Disease:

Schizophrenia

0.700

GeneticVariation

GWASCAT

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.

31374203

2019

dbSNP:

rs2966157

Entrez Id:	23042;54700
Gene Symbol:	PDXDC1;RRN3

PDXDC1;RRN3

CUI:	C0021704
Disease:

Intelligence

0.700

GeneticVariation

GWASCAT

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.

31374203

2019

dbSNP:

rs34614532

Entrez Id:	23042;123803
Gene Symbol:	PDXDC1;NTAN1

PDXDC1;NTAN1

CUI:	C0005890
Disease:

Body Height

0.700

GeneticVariation

GWASCAT

Characterizing rare and low-frequency height-associated variants in the Japanese population.

31562340

2019

dbSNP:

rs3803573

Entrez Id:	23042;123803
Gene Symbol:	PDXDC1;NTAN1

PDXDC1;NTAN1

CUI:	C0424678
Disease:

Lean body mass

0.700

GeneticVariation

GWASCAT

Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.

30593698

2019

dbSNP:

rs4985155

Entrez Id:	23042
Gene Symbol:	PDXDC1

PDXDC1

CUI:	C1305855
Disease:

Body mass index

0.700

GeneticVariation

GWASCAT

Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.

30239722

2019

dbSNP:

rs11644601

Entrez Id:	23042;54700
Gene Symbol:	PDXDC1;RRN3

PDXDC1;RRN3

CUI:	C0392885
Disease:

High density lipoprotein measurement

0.700

GeneticVariation

GWASCAT

A large electronic-health-record-based genome-wide study of serum lipids.

29507422

2018

dbSNP:

rs11644601

Entrez Id:	23042;54700
Gene Symbol:	PDXDC1;RRN3

PDXDC1;RRN3

CUI:	C0202236
Disease:

Triglycerides measurement

0.700

GeneticVariation

GWASCAT

A large electronic-health-record-based genome-wide study of serum lipids.

29507422

2018

dbSNP:

rs12928099

Entrez Id:	23042;123803
Gene Symbol:	PDXDC1;NTAN1

PDXDC1;NTAN1

CUI:	C0202236
Disease:

Triglycerides measurement

0.700

GeneticVariation

GWASCAT

Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.

30275531

2018

dbSNP:

rs35574015

Entrez Id:	23042;123803
Gene Symbol:	PDXDC1;NTAN1

PDXDC1;NTAN1

CUI:	C0022661
Disease:

Kidney Failure, Chronic

0.700

GeneticVariation

GWASCAT

Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.

29545352

2018

dbSNP:

rs35574015

Entrez Id:	23042;123803
Gene Symbol:	PDXDC1;NTAN1

PDXDC1;NTAN1

CUI:	C1561643
Disease:

Chronic Kidney Diseases

0.700

GeneticVariation

GWASCAT

Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.

29545352

2018

dbSNP:

rs7200543

Entrez Id:	23042
Gene Symbol:	PDXDC1

PDXDC1

CUI:	C1305855
Disease:

Body mass index

0.700

GeneticVariation

GWASCAT

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

29273807

2018

dbSNP:

rs7200543

Entrez Id:	23042
Gene Symbol:	PDXDC1

PDXDC1

CUI:	C1305855
Disease:

Body mass index

0.700

GeneticVariation

GWASCAT

A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.

30108127

2018

dbSNP:

rs11376559

Entrez Id:	23042;123803
Gene Symbol:	PDXDC1;NTAN1

PDXDC1;NTAN1

CUI:	C0455829
Disease:

Waist Circumference

0.700

GeneticVariation

GWASCAT

Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits.

28552196

2017

dbSNP:

rs7200543

Entrez Id:	23042
Gene Symbol:	PDXDC1

PDXDC1

CUI:	C1305855
Disease:

Body mass index

0.700

GeneticVariation

GWASCAT

Genome-wide association study identifies 112 new loci for body mass index in the Japanese population.

28892062

2017

dbSNP:

rs7200543

Entrez Id:	23042
Gene Symbol:	PDXDC1

PDXDC1

CUI:	C0202236
Disease:

Triglycerides measurement

0.700

GeneticVariation

GWASCAT

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.

28334899

2017

dbSNP:

rs11644601

Entrez Id:	23042;54700
Gene Symbol:	PDXDC1;RRN3

PDXDC1;RRN3

CUI:	C0523744
Disease:

Lipids measurement

0.700

GeneticVariation

GWASCAT

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.

27005778

2016

dbSNP:

rs4985155

Entrez Id:	23042
Gene Symbol:	PDXDC1

PDXDC1

CUI:	C1305855
Disease:

Body mass index

0.700

GeneticVariation

GWASCAT

Genetic studies of body mass index yield new insights for obesity biology.

25673413

2015