SIRT1, sirtuin 1, 23411

N. diseases: 675; N. variants: 21
Disease: Diabetes ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7896005
rs7896005
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
CUI: C0011847
Disease:
Diabetes 		0.010 GeneticVariation BEFREE Among metabolically characterized subjects with normal glucose tolerance (N=243), those carrying the diabetes risk allele (T) for rs10509291 and (G) for rs7896005 had a reduced acute insulin response (AIR) to an intravenous glucose bolus (adjusted P=0.045 and 0.035, respectively). 21871827 2011