SYT14, synaptotagmin 14, 255928

N. diseases: 34; N. variants: 8
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2205986
rs2205986
Entrez Id: 255928
Gene Symbol: SYT14
SYT14
CUI: C0026769
Disease:
Multiple Sclerosis 		0.710 GeneticVariation BEFREE Analysis of an independent cohort of IFN-β-treated MS patients identified via electronic medical records showed that rs2205986 was also associated with increased peak levels of aspartate aminotransferase (P = 7.6 × 10<sup>-5</sup>) and alkaline phosphatase (P = 4.9 × 10<sup>-4</sup>). 30013178 2018
dbSNP: rs2205986
rs2205986
Entrez Id: 255928
Gene Symbol: SYT14
SYT14
CUI: C0026769
Disease:
Multiple Sclerosis 		0.710 GeneticVariation GWASCAT Analysis of an independent cohort of IFN-β-treated MS patients identified via electronic medical records showed that rs2205986 was also associated with increased peak levels of aspartate aminotransferase (P = 7.6 × 10<sup>-5</sup>) and alkaline phosphatase (P = 4.9 × 10<sup>-4</sup>). 30013178 2018
dbSNP: rs2046850
rs2046850
Entrez Id: 255928
Gene Symbol: SYT14
SYT14
CUI: C0011334
Disease:
Dental caries 		T 0.700 GeneticVariation GWASCAT Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data. 31235808 2019
dbSNP: rs6540578
rs6540578
Entrez Id: 255928
Gene Symbol: SYT14
SYT14
CUI: C0042834
Disease:
Vital capacity 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs6661316
rs6661316
Entrez Id: 255928
Gene Symbol: SYT14
SYT14
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs6695101
rs6695101
Entrez Id: 255928
Gene Symbol: SYT14
SYT14
CUI: C1305855
Disease:
Body mass index 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs2205986
rs2205986
Entrez Id: 255928
Gene Symbol: SYT14
SYT14
CUI: C4277682
Disease:
Chemical and Drug Induced Liver Injury 		0.700 GeneticVariation GWASCAT Common variation near IRF6 is associated with IFN-β-induced liver injury in multiple sclerosis. 30013178 2018
dbSNP: rs9429830
rs9429830
Entrez Id: 255928
Gene Symbol: SYT14
SYT14
CUI: C0008924
Disease:
Cleft upper lip 		0.700 GeneticVariation GWASDB Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. 22863734 2012
dbSNP: rs387907033
rs387907033
Entrez Id: 255928
Gene Symbol: SYT14
SYT14
CUI: C3280226
Disease:
SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 11 		0.700 GeneticVariation UNIPROT Exome sequencing reveals a homozygous SYT14 mutation in adult-onset, autosomal-recessive spinocerebellar ataxia with psychomotor retardation. 21835308 2011
dbSNP: rs11119388
rs11119388
Entrez Id: 255928
Gene Symbol: SYT14
SYT14
CUI: C0008924
Disease:
Cleft upper lip 		0.700 GeneticVariation GWASDB A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4. 20436469 2010