GPR35, G protein-coupled receptor 35, 2859

N. diseases: 102; N. variants: 4
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4676410
rs4676410
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0008313
Disease:
Cholangitis, Sclerosing 		A 0.800 GeneticVariation GWASDB Genome-wide association analysis in primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4. 22821403 2013
dbSNP: rs4676410
rs4676410
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0008313
Disease:
Cholangitis, Sclerosing 		A 0.800 GeneticVariation GWASCAT Genome-wide association analysis in primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4. 22821403 2013
dbSNP: rs3749171
rs3749171
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		T 0.800 GeneticVariation GWASDB Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. 23128233 2012
dbSNP: rs3749171
rs3749171
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		T 0.800 GeneticVariation GWASCAT Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. 23128233 2012
dbSNP: rs3749171
rs3749171
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0009324
Disease:
Ulcerative Colitis 		0.710 GeneticVariation BEFREE The T108M polymorphism is associated with ulcerative colitis and primary sclerosing cholangitis, inflammatory diseases with a high cancer risk. 30600262 2019
dbSNP: rs3749171
rs3749171
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0009324
Disease:
Ulcerative Colitis 		T 0.710 GeneticVariation GWASCAT Enhanced Contribution of HLA in Pediatric Onset Ulcerative Colitis. 29562276 2018
dbSNP: rs3749171
rs3749171
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0009324
Disease:
Ulcerative Colitis 		0.710 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs3749171
rs3749171
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0009324
Disease:
Ulcerative Colitis 		A 0.710 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015
dbSNP: rs3749172
rs3749172
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0010346
Disease:
Crohn Disease 		A 0.710 GeneticVariation GWASCAT We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15. 25489960 2015
dbSNP: rs3749172
rs3749172
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0010346
Disease:
Crohn Disease 		0.710 GeneticVariation BEFREE We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15. 25489960 2015
dbSNP: rs4676410
rs4676410
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		0.710 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015
dbSNP: rs4676410
rs4676410
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		0.710 GeneticVariation BEFREE We have identified five new regions associated with early-onset IBD susceptibility, including 16p11 near the cytokine gene IL27 (rs8049439, P = 2.41 x 10(-9)), 22q12 (rs2412973, P = 1.55 x 10(-9)), 10q22 (rs1250550, P = 5.63 x 10(-9)), 2q37 (rs4676410, P = 3.64 x 10(-8)) and 19q13.11 (rs10500264, P = 4.26 x 10(-10)). 19915574 2009
dbSNP: rs4676410
rs4676410
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0200638
Disease:
Eosinophil count procedure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs34236350
rs34236350
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0750880
Disease:
Monocyte count result 		T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs34236350
rs34236350
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0200637
Disease:
Monocyte count procedure 		T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs3749171
rs3749171
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0038013
Disease:
Ankylosing spondylitis 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs3749171
rs3749171
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0010346
Disease:
Crohn Disease 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs3749171
rs3749171
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0008313
Disease:
Cholangitis, Sclerosing 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs3749171
rs3749171
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0033860
Disease:
Psoriasis 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs4676410
rs4676410
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0010346
Disease:
Crohn Disease 		A 0.700 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688 2015
dbSNP: rs4676410
rs4676410
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0009324
Disease:
Ulcerative Colitis 		A 0.700 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688 2015
dbSNP: rs4676410
rs4676410
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0007570
Disease:
Celiac Disease 		A 0.700 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688 2015
dbSNP: rs4676410
rs4676410
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C3150797
Disease:
AUTOIMMUNE DISEASE, SUSCEPTIBILITY TO, 6 		A 0.700 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688 2015
dbSNP: rs4676410
rs4676410
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		A 0.700 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688 2015
dbSNP: rs4676410
rs4676410
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
CUI: C0038013
Disease:
Ankylosing spondylitis 		A 0.700 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688 2015