|
rs1800872
|
IL10;IL19
|
Brucellosis
|
|
0.010 |
GeneticVariation |
BEFREE |
IL-4 rs2243250 and IL-18 rs1946519 have a positive correlation with brucellosis whereas the IFN-γ UTR5644, TGF-β rs1800470 and rs1800471, TNF-α rs1800629, and IL-10 rs1800872 showed a negative association with this disease.
|
31816580 |
2020 |
|
rs1800872
|
IL10;IL19
|
Pemphigus Vulgaris
|
|
0.010 |
GeneticVariation |
BEFREE |
Among the large number of studied SNPs, it was found that several SNPs in different genes might control the susceptibility of PV, including TNFA (rs361525, rs1800629, rs1800629), IL10 (rs1800871, rs1800896, rs1800871, and rs1800872), IL6 (rs1800795), CTLA4 (rs231775), ICOS (rs10932029), CD86 (rs1129055), DSG3 (rs8085532, rs3911655, rs3848485, rs3794925, rs1466379), ST18 (rs2304365, rs17315309) and TAP2 (rs7454108), probably in a population-specific manner.
|
31342641 |
2020 |
|
rs1800896
|
IL10;IL19
|
Superficial ulcer
|
|
0.010 |
GeneticVariation |
BEFREE |
Finally, we verified higher IL-6 value in the RA patients than healthy control group (p = 0.007) and an association between high IL-6 levels and increased CDAI (r = 0.4648, p = 0.0015); DAS 28 (r = 0.3933, p= 0.0091), presence of bone erosions (r = 0.3170, p = 0.0361), ESR levels(r = 0.3041, p = 0.0448) and IFN-γ levels (r = 0.3049, p = 0.0468).Altogether, we suggest that IL10 -1082 (T>C, rs1800896) and INFG -1616(A>G, rs2069705) polymorphisms as well as IL-6 levels alterations may play a role for prognostic and disease follow-up.
|
31494241 |
2020 |
|
rs1800871
|
IL10;IL19
|
Periodontitis
|
|
0.010 |
GeneticVariation |
BEFREE |
The studies reviewed support that the IL-10 rs1800871 and rs1800872 polymorphisms may represent a potential genetic biomarker for periodontitis risk in Latin American populations.
|
30343215 |
2019 |
|
rs1800871
|
IL10;IL19
|
Behcet's uveitis
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>Results</i>: The risk allele, A, in rs1800871, of <i>IL-10</i> gene was highly prevalent in Behcet's uveitis and healthy control samples alike; highest among the Turkish groups.
|
29792538 |
2019 |
|
rs1800871
|
IL10;IL19
|
Rhegmatogenous retinal detachment
|
|
0.010 |
GeneticVariation |
BEFREE |
Differences in genotype distributions between patients with RRD with or without PVR were detected in rs1800795 (IL6) (P = 0.04), rs1800871 (in the vicinity of the IL10) (P = 0.034), and rs1800471 (TGFB1) (P = 0.032).
|
30807515 |
2019 |
|
rs1800871
|
IL10;IL19
|
Chronic Periodontitis
|
|
0.010 |
GeneticVariation |
BEFREE |
The -819C>T(rs1800871) and -592C>A(rs1800872) polymorphisms were both associated with increased CP risk in Latinos under the allele and dominant models.
|
30295312 |
2019 |
|
rs1800871
|
IL10;IL19
|
Proliferative vitreoretinopathy
|
|
0.010 |
GeneticVariation |
BEFREE |
Differences in genotype distributions between patients with RRD with or without PVR were detected in rs1800795 (IL6) (P = 0.04), rs1800871 (in the vicinity of the IL10) (P = 0.034), and rs1800471 (TGFB1) (P = 0.032).
|
30807515 |
2019 |
|
rs1800871
|
IL10;IL19
|
Gestational Diabetes
|
|
0.010 |
GeneticVariation |
BEFREE |
This study aimed to investigate the association between IL-10 gene rs1800896 (-1082 A/G), rs1800871 (-819 T/C), rs1800872 (-592 A/C), and rs3021094 (3388 A/C) single nucleotide polymorphisms (SNPs) and GDM susceptibility.
|
30873205 |
2019 |
|
rs1800871
|
IL10;IL19
|
Lupus Erythematosus, Systemic
|
|
0.010 |
GeneticVariation |
BEFREE |
Interleukin 10 gene promoter polymorphisms (rs1800896, rs1800871 and rs1800872) and haplotypes are associated with the activity of systemic lupus erythematosus and IL10 levels in an Iranian population.
|
30430731 |
2019 |
|
rs1800871
|
IL10;IL19
|
Tuberculosis, Spinal
|
|
0.010 |
GeneticVariation |
BEFREE |
CONCLUSIONS The rs1800871 (A/G) polymorphism in IL-10 gene is related to the susceptibility to spinal tuberculosis.
|
31264664 |
2019 |
|
rs1800872
|
IL10;IL19
|
Periodontal Diseases
|
|
0.010 |
GeneticVariation |
BEFREE |
No precise consensus has been reached to evaluate the association between the IL-10 rs1800872 (- 592, -590, -597 C>A) polymorphism and periodontal disease.
|
31577700 |
2019 |
|
rs1800872
|
IL10;IL19
|
Lupus Erythematosus, Systemic
|
|
0.010 |
GeneticVariation |
BEFREE |
Interleukin 10 gene promoter polymorphisms (rs1800896, rs1800871 and rs1800872) and haplotypes are associated with the activity of systemic lupus erythematosus and IL10 levels in an Iranian population.
|
30430731 |
2019 |
|
rs1800872
|
IL10;IL19
|
Coronary heart disease
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of IL-8-251 A/T rs4073 and IL-10 rs1800872 -592C/A Polymorphisms and Coronary Artery Disease in North Indian Population.
|
30073578 |
2019 |
|
rs1800872
|
IL10;IL19
|
Psoriasis
|
|
0.010 |
GeneticVariation |
BEFREE |
Current published studies fail to support an association of the IL-1RN VNTR polymorphism and IL-10 SNPs rs1800896, rs3021097, and rs1800872 with psoriasis risk.
|
30523673 |
2019 |
|
rs1800872
|
IL10;IL19
|
Coronary Artery Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of IL-8-251 A/T rs4073 and IL-10 rs1800872 -592C/A Polymorphisms and Coronary Artery Disease in North Indian Population.
|
30073578 |
2019 |
|
rs1800872
|
IL10;IL19
|
Coronary Arteriosclerosis
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of IL-8-251 A/T rs4073 and IL-10 rs1800872 -592C/A Polymorphisms and Coronary Artery Disease in North Indian Population.
|
30073578 |
2019 |
|
rs1800872
|
IL10;IL19
|
Filarial Elephantiases
|
|
0.010 |
GeneticVariation |
BEFREE |
We evaluated the frequency of alleles and genotypes of <i>IL-10</i> (rs3024496, rs1800872), <i>IL-10RA</i> (rs3135932), <i>IL-10RB</i> (rs2834167), <i>PD-1</i> (rs2227982, rs10204525), <i>PD-L1</i> (rs4143815), <i>PD-L2</i> (rs7854413), and single-nucleotide polymorphisms (SNPs) in 103 patients with chronic pathology (CP), such as elephantiasis or hydrocele and 106 endemic normal (EN) individuals from a South Indian population living in an area endemic for LF.
|
30594267 |
2019 |
|
rs1800896
|
IL10;IL19
|
Pain
|
|
0.010 |
GeneticVariation |
BEFREE |
IL-10 rs1800896 C allele is correlated with higher IL-10 levels in the plasma and the PBMC culture supernatant, which is associated with a higher pain threshold in the Chinese patients with IBS-D.
|
31205078 |
2019 |
|
rs1800896
|
IL10;IL19
|
Periodontitis
|
|
0.010 |
GeneticVariation |
BEFREE |
No significant association was observed between rs1800896 and periodontitis risk.
|
30343215 |
2019 |
|
rs1800896
|
IL10;IL19
|
Overactive Bladder
|
|
0.010 |
GeneticVariation |
BEFREE |
However, allele A of rs1800896 (1082bp upstream) was associated with protection against neurological impairment, specifically overactive bladder (OR=0.447, 95% CI 0.28-0.70, p=0.001).
|
31166487 |
2019 |
|
rs1800896
|
IL10;IL19
|
Cerebral Infarction
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, IL-10 rs1800896 polymorphism was also significantly associated with individual susceptibility to IS, especially for CI.
|
31446341 |
2019 |
|
rs1800896
|
IL10;IL19
|
Kidney Failure, Acute
|
|
0.010 |
GeneticVariation |
BEFREE |
Despite the numerous, although contradictory, studies about association between polymorphisms rs1800629 in <i>TNFA</i> and rs1800896 in <i>IL10</i> and AKI, we found no association (odds ratios 1.06 (95% CI 0.89⁻1.28, <i>p</i> = 0.51) and 0.92 (95% CI 0.80⁻1.05, <i>p</i> = 0.20), respectively).
|
30862128 |
2019 |
|
rs1800896
|
IL10;IL19
|
Chronic Periodontitis
|
|
0.010 |
GeneticVariation |
BEFREE |
The present meta-analysis suggests that the -1082A>G(rs1800896) polymorphism might be a protective factor for CP in both Caucasians and Latinos, but the -819C>T(rs1800871) and -592C>A(rs1800872) polymorphisms might contribute to CP pathogenesis in Latinos.
|
30295312 |
2019 |
|
rs2222202
|
IL10;IL19
|
Nephritis, Interstitial
|
|
0.010 |
GeneticVariation |
BEFREE |
The homozygous minor allele in IL-10 +434T (rs2222202) and IL-10+504G (rs3024490) was found in all patients with TIN or TINU syndrome while the frequency of these minor alleles in the control population was 44% and 23%, respectively (p <0.001).
|
30779760 |
2019 |