HTR4, 5-hydroxytryptamine receptor 4, 3360

N. diseases: 80; N. variants: 26
Disease: Chronic Obstructive Airway Disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10037493
rs10037493
Entrez Id: 3360;107986462
Gene Symbol: HTR4;LOC107986462
HTR4;LOC107986462
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease 		C 0.700 GeneticVariation GWASCAT Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations. 30804561 2019
dbSNP: rs7733088
rs7733088
Entrez Id: 3360;107986462
Gene Symbol: HTR4;LOC107986462
HTR4;LOC107986462
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease 		0.700 GeneticVariation GWASCAT Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis. 30940143 2019
dbSNP: rs7733088
rs7733088
Entrez Id: 3360;107986462
Gene Symbol: HTR4;LOC107986462
HTR4;LOC107986462
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease 		G 0.700 GeneticVariation GWASCAT Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. 28166215 2017
dbSNP: rs3995090
rs3995090
Entrez Id: 3360;107986462
Gene Symbol: HTR4;LOC107986462
HTR4;LOC107986462
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease 		0.010 GeneticVariation BEFREE The SNP (rs3995090) in HTR4 was associated with COPD (adjusted P = 0.022) in never-smokers, and the SNP (rs2070600) in AGER was associated with forced expiratory volume in 1 s (FEV1 %) predicted (β = -0.066, adjusted P = 0.016) and FEV1 /forced vital capacity (β = -0.071, adjusted P = 0.009) in all subjects. 24286382 2014