IFI27, interferon alpha inducible protein 27, 3429

N. diseases: 332; N. variants: 4
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs544899118
rs544899118
Entrez Id: 3429
Gene Symbol: IFI27
IFI27
CUI: C1168401
Disease:
Squamous cell carcinoma of the head and neck 		0.010 GeneticVariation BEFREE These results suggest that p27 T109G polymorphism individually or in combination with p21 (C98A and C70T) polymorphisms increases risk of SPM in patients with index SCCHN. 22449259 2012
dbSNP: rs544899118
rs544899118
Entrez Id: 3429
Gene Symbol: IFI27
IFI27
CUI: C2678061
Disease:
SCAPULOPERONEAL MYOPATHY, X-LINKED DOMINANT 		0.010 GeneticVariation BEFREE These results suggest that p27 T109G polymorphism individually or in combination with p21 (C98A and C70T) polymorphisms increases risk of SPM in patients with index SCCHN. 22449259 2012
dbSNP: rs765502229
rs765502229
Entrez Id: 3429
Gene Symbol: IFI27
IFI27
CUI: C0001206
Disease:
Acromegaly 		0.010 GeneticVariation BEFREE The I119T substitution occurred in a female patient with acromegaly. p27(I119T) shows an abnormal migration pattern by SDS-PAGE. 22291433 2012
dbSNP: rs765318806
rs765318806
Entrez Id: 3429
Gene Symbol: IFI27
IFI27
CUI: C0002736
Disease:
Amyotrophic Lateral Sclerosis 		0.010 GeneticVariation BEFREE G93A SOD1 alters cell cycle in a cellular model of Amyotrophic Lateral Sclerosis. 20561900 2010
dbSNP: rs886547387
rs886547387
Entrez Id: 3429
Gene Symbol: IFI27
IFI27
CUI: C0027651
Disease:
Neoplasms 		0.010 GeneticVariation BEFREE Moreover, we also demonstrate that Skp2 has oncogenic potential by showing that Skp2 cooperates with H-Ras(G12V) to malignantly transform primary rodent fibroblasts as scored by colony formation in soft agar and tumor formation in nude mice. 11309491 2001