IRGM, immunity related GTPase M, 345611

N. diseases: 57; N. variants: 13
Disease: Inflammatory Bowel Diseases ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11741861
rs11741861
Entrez Id: 91975;345611
Gene Symbol: ZNF300;IRGM
ZNF300;IRGM
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		0.800 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908 2017
dbSNP: rs11741861
rs11741861
Entrez Id: 91975;345611
Gene Symbol: ZNF300;IRGM
ZNF300;IRGM
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		G 0.800 GeneticVariation GWASDB Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. 23128233 2012
dbSNP: rs11741861
rs11741861
Entrez Id: 91975;345611
Gene Symbol: ZNF300;IRGM
ZNF300;IRGM
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		G 0.800 GeneticVariation GWASCAT Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. 23128233 2012
dbSNP: rs10065172
rs10065172
Entrez Id: 345611
Gene Symbol: IRGM
IRGM
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		0.010 GeneticVariation BEFREE Susceptibility to Crohn disease (CD), an inflammatory bowel disease, is influenced by common variants at many loci like the exonic synonymous IRGM SNP (rs10065172, NM_001145805.1, c.313C>T). 21508684 2011
dbSNP: rs4958847
rs4958847
Entrez Id: 345611
Gene Symbol: IRGM
IRGM
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		0.010 GeneticVariation BEFREE NCF4 and IRGM were significantly associated with ileal CD (P-value(rs4821544)=0.0090, odds ratio (OR)=1.425, 95% confidence interval (CI): 1.092-1.859; P-value(rs13361189)=0.0017, OR=1.942, 95% CI: 1.274-2.959; P-value(rs4958847)=0.0022, OR=1.767, 95% CI: 1.224-2.558), but not with other forms of inflammatory bowel disease (IBD). 18580884 2008