IL1B, interleukin 1 beta, 3553

N. diseases: 1801; N. variants: 22
Disease: Depressive disorder ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs16944
rs16944
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0011581
Disease:
Depressive disorder 		0.020 GeneticVariation BEFREE Considering the inflammatory-depression link, and that women are twice as likely to experience depression compared to men, the current study (<i>N</i> = 475 university students) examined the moderating role of three independent cytokine single nucleotide polymorphisms (SNPs; IL-1β rs16944, IL-6 rs1800795 SNP, TNF-α rs1800629) in the relationship between early-life adversity and depressive symptoms, and whether these relations differed between males and females. 30967802 2019
dbSNP: rs16944
rs16944
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0011581
Disease:
Depressive disorder 		0.020 GeneticVariation BEFREE We also demonstrated that the presence of exposure to childhood adversity changed the direction of the rs16944 effect on depression phenotype. 26891860 2016