IL5, interleukin 5, 3567

N. diseases: 359; N. variants: 9
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1986009
rs1986009
Entrez Id: 3567
Gene Symbol: IL5
IL5
CUI: C0004096
Disease:
Asthma 		A 0.700 GeneticVariation GWASCAT Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study. 30552067 2019
dbSNP: rs2078387
rs2078387
Entrez Id: 3567
Gene Symbol: IL5
IL5
CUI: C0200638
Disease:
Eosinophil count procedure 		0.700 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs377260382
rs377260382
Entrez Id: 3567;10111
Gene Symbol: IL5;RAD50
IL5;RAD50
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 GeneticVariation CLINVAR Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic. 26023681 2015
dbSNP: rs377260382
rs377260382
Entrez Id: 3567;10111
Gene Symbol: IL5;RAD50
IL5;RAD50
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 GeneticVariation CLINVAR Detection of novel germline mutations for breast cancer in non-BRCA1/2 families. 26094658 2015
dbSNP: rs876658212
rs876658212
Entrez Id: 3567;10111
Gene Symbol: IL5;RAD50
IL5;RAD50
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		G 0.700 GeneticVariation CLINVAR Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic. 26023681 2015
dbSNP: rs876658212
rs876658212
Entrez Id: 3567;10111
Gene Symbol: IL5;RAD50
IL5;RAD50
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		G 0.700 GeneticVariation CLINVAR Detection of novel germline mutations for breast cancer in non-BRCA1/2 families. 26094658 2015
dbSNP: rs1339714611
rs1339714611
Entrez Id: 3567;10111
Gene Symbol: IL5;RAD50
IL5;RAD50
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder. 19409520 2009
dbSNP: rs587781625
rs587781625
Entrez Id: 3567;10111
Gene Symbol: IL5;RAD50
IL5;RAD50
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		TA 0.700 CausalMutation CLINVAR Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder. 19409520 2009
dbSNP: rs748086984
rs748086984
Entrez Id: 3567;10111
Gene Symbol: IL5;RAD50
IL5;RAD50
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 GeneticVariation CLINVAR Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder. 19409520 2009
dbSNP: rs1339714611
rs1339714611
Entrez Id: 3567;10111
Gene Symbol: IL5;RAD50
IL5;RAD50
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Evaluation of RAD50 in familial breast cancer predisposition. 16385572 2006
dbSNP: rs587781625
rs587781625
Entrez Id: 3567;10111
Gene Symbol: IL5;RAD50
IL5;RAD50
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		TA 0.700 CausalMutation CLINVAR Evaluation of RAD50 in familial breast cancer predisposition. 16385572 2006
dbSNP: rs748086984
rs748086984
Entrez Id: 3567;10111
Gene Symbol: IL5;RAD50
IL5;RAD50
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 GeneticVariation CLINVAR Evaluation of RAD50 in familial breast cancer predisposition. 16385572 2006
dbSNP: rs377260382
rs377260382
Entrez Id: 3567;10111
Gene Symbol: IL5;RAD50
IL5;RAD50
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 GeneticVariation CLINVAR Molecular cloning and characterization of splice variants of human RAD50 gene. 10415333 1999
dbSNP: rs1554096644
rs1554096644
Entrez Id: 3567;10111
Gene Symbol: IL5;RAD50
IL5;RAD50
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 CausalMutation CLINVAR
dbSNP: rs2069812
rs2069812
Entrez Id: 3567
Gene Symbol: IL5
IL5
CUI: C0079731
Disease:
B-Cell Lymphomas 		0.010 GeneticVariation BEFREE A significant interaction with BMI was only observed for IFNGR2 (rs9808753 P(forinteraction) = .034) and IL7R (rs1494555 P(forinteraction) = .016) for NHL overall; IL7R (rs1494555 P(forinteraction) = .016) and TNF (1799724 P(forinteraction) = .031) for B-cell lymphoma; and IL5 (rs2069812 P(forinteraction) = .034) for T-cell lymphoma. 20952689 2011
dbSNP: rs2069812
rs2069812
Entrez Id: 3567
Gene Symbol: IL5
IL5
CUI: C0079772
Disease:
T-Cell Lymphoma 		0.010 GeneticVariation BEFREE A significant interaction with BMI was only observed for IFNGR2 (rs9808753 P(forinteraction) = .034) and IL7R (rs1494555 P(forinteraction) = .016) for NHL overall; IL7R (rs1494555 P(forinteraction) = .016) and TNF (1799724 P(forinteraction) = .031) for B-cell lymphoma; and IL5 (rs2069812 P(forinteraction) = .034) for T-cell lymphoma. 20952689 2011
dbSNP: rs2069812
rs2069812
Entrez Id: 3567
Gene Symbol: IL5
IL5
CUI: C0024305
Disease:
Lymphoma, Non-Hodgkin 		0.010 GeneticVariation BEFREE A significant interaction with BMI was only observed for IFNGR2 (rs9808753 P(forinteraction) = .034) and IL7R (rs1494555 P(forinteraction) = .016) for NHL overall; IL7R (rs1494555 P(forinteraction) = .016) and TNF (1799724 P(forinteraction) = .031) for B-cell lymphoma; and IL5 (rs2069812 P(forinteraction) = .034) for T-cell lymphoma. 20952689 2011
dbSNP: rs2069812
rs2069812
Entrez Id: 3567
Gene Symbol: IL5
IL5
CUI: C0018213
Disease:
Graves Disease 		0.010 GeneticVariation BEFREE The results suggested that the polymorphism of IL-3 (rs40401) and IL-5 (rs2069812) were associated with GD and GO susceptibility in Chinese population. 20332709 2010
dbSNP: rs2069812
rs2069812
Entrez Id: 3567
Gene Symbol: IL5
IL5
CUI: C0339143
Disease:
Thyroid associated opthalmopathies 		0.010 GeneticVariation BEFREE The results suggested that the polymorphism of IL-3 (rs40401) and IL-5 (rs2069812) were associated with GD and GO susceptibility in Chinese population. 20332709 2010