|
rs115008099
|
IL13;TH2LCRR
|
Respiratory Tract Diseases
|
|
0.700 |
GeneticVariation |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
rs115008099
|
IL13;TH2LCRR
|
Asthma
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.
|
31619474 |
2019 |
|
rs12188917
|
IL13;TH2LCRR
|
Dermatitis, Atopic
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.
|
26482879 |
2015 |
|
rs1295685
|
IL13;TH2LCRR
|
Psoriasis
|
G |
0.800 |
GeneticVariation |
GWASCAT |
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.
|
23143594 |
2012 |
|
rs1295685
|
IL13;TH2LCRR
|
Psoriasis
|
|
0.800 |
GeneticVariation |
GWASDB |
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.
|
23143594 |
2012 |
|
rs1295685
|
IL13;TH2LCRR
|
Childhood asthma
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.
|
29273806 |
2018 |
|
rs1295685
|
IL13;TH2LCRR
|
Psoriasis vulgaris
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
|
26626624 |
2015 |
|
rs1295685
|
IL13;TH2LCRR
|
Dermatitis, Atopic
|
A |
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.
|
23886662 |
2013 |
|
rs1295685
|
IL13;TH2LCRR
|
Eczema
|
|
0.700 |
GeneticVariation |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
rs1295685
|
IL13;TH2LCRR
|
Chronic Obstructive Airway Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
IL13 SNPs rs2066960(intron 1), rs20541(R130Q) and rs1295685(exon 4) were associated with COPD risk and lower baseline lung function in the recessive model.
|
19796199 |
2010 |
|
rs1295685
|
IL13;TH2LCRR
|
Asthma
|
|
0.010 |
GeneticVariation |
BEFREE |
IL13 Arg130Gln (rs20541) and G870A (rs1295685) were consistently associated with asthma and serum IgE in both asthma populations.
|
20484924 |
2010 |
|
rs1295686
|
IL13;TH2LCRR
|
Asthma
|
|
0.840 |
GeneticVariation |
BEFREE |
There are controversies on the association between interleukin-13 (IL-13) +1923C/T polymorphism (rs1295686) and the risk of asthma.
|
23841068 |
2013 |
|
rs1295686
|
IL13;TH2LCRR
|
Asthma
|
T |
0.840 |
GeneticVariation |
GWASDB |
A large-scale, consortium-based genomewide association study of asthma.
|
20860503 |
2010 |
|
rs1295686
|
IL13;TH2LCRR
|
Asthma
|
T |
0.840 |
GeneticVariation |
GWASCAT |
A large-scale, consortium-based genomewide association study of asthma.
|
20860503 |
2010 |
|
rs1295686
|
IL13;TH2LCRR
|
Asthma
|
|
0.840 |
GeneticVariation |
GWASDB |
Genome-wide association study to identify genetic determinants of severe asthma.
|
22561531 |
2012 |
|
rs1295686
|
IL13;TH2LCRR
|
Asthma
|
|
0.840 |
GeneticVariation |
BEFREE |
IL13_rs1295686 was associated with all asthma (OR 1.64, 95% CI 1.16-2.32) and early-onset asthma (OR 1.92, 95% CI 1.20-3.06) in adults, whereas GSDMB_rs2305480 was only associated with early-onset asthma (OR 0.69, 95% CI 0.49-0.96).
|
26534891 |
2016 |
|
rs1295686
|
IL13;TH2LCRR
|
Asthma
|
|
0.840 |
GeneticVariation |
GWASDB |
Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.
|
21907864 |
2011 |
|
rs1295686
|
IL13;TH2LCRR
|
Asthma
|
|
0.840 |
GeneticVariation |
BEFREE |
IL-13 minor T and A alleles for rs1295686 and rs20541, respectively, were associated with significantly higher risk of asthma in the Saudi Arabian population.
|
29211635 |
2018 |
|
rs1295686
|
IL13;TH2LCRR
|
Asthma
|
|
0.840 |
GeneticVariation |
BEFREE |
We conducted an association study by genotyping four SNPs (rs2244012 and rs6871536 in RAD50 as well as rs1295686 and rs1800925 in IL13) in 652 asthmatic children and age-matched 752 healthy controls from Northeastern Han Chinese to evaluate the asthma susceptibility with each individual SNP using SNaPshot genotyping method.
|
26365633 |
2016 |
|
rs1295686
|
IL13;TH2LCRR
|
Dermatitis, Atopic
|
T |
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms.
|
25574825 |
2015 |
|
rs1295686
|
IL13;TH2LCRR
|
Dermatitis, Atopic
|
A |
0.800 |
GeneticVariation |
GWASCAT |
A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.
|
23886662 |
2013 |
|
rs1295686
|
IL13;TH2LCRR
|
Dermatitis, Atopic
|
A |
0.800 |
GeneticVariation |
GWASDB |
A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.
|
23886662 |
2013 |
|
rs1295686
|
IL13;TH2LCRR
|
Allergic Reaction
|
|
0.700 |
GeneticVariation |
GWASCAT |
Detection and interpretation of shared genetic influences on 42 human traits.
|
27182965 |
2016 |
|
rs1295686
|
IL13;TH2LCRR
|
Sleep onset Insomnia
|
|
0.010 |
GeneticVariation |
BEFREE |
After adjusting for genomic estimates of ancestry, self-reported race/ethnicity and viral load, SOI was associated with higher IL-13 plasma levels and with six single nucleotide polymorphisms (SNPs): IL1B rs1143642 and rs1143623, IL6 rs4719714, IL13 rs1295686, NFKB1 rs4648110, and TNFA rs2857602.
|
25535857 |
2015 |
|
rs1295686
|
IL13;TH2LCRR
|
IgE-mediated food allergy
|
|
0.010 |
GeneticVariation |
BEFREE |
We show for the first time, in two independent cohorts, that IL13 polymorphism rs1295686 (in complete linkage disequilibrium with functional variant rs20541) is associated with challenge-proven food allergy.
|
28544327 |
2017 |