ITGB5, integrin subunit beta 5, 3693

N. diseases: 43; N. variants: 6
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11928547
rs11928547
Entrez Id: 3693
Gene Symbol: ITGB5
ITGB5
CUI: C0871470
Disease:
Systolic Pressure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs3772840
rs3772840
Entrez Id: 3693
Gene Symbol: ITGB5
ITGB5
CUI: C0871470
Disease:
Systolic Pressure 		T 0.700 GeneticVariation GWASCAT Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. 30578418 2019
dbSNP: rs9875516
rs9875516
Entrez Id: 3693
Gene Symbol: ITGB5
ITGB5
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs4141663
rs4141663
Entrez Id: 3693
Gene Symbol: ITGB5
ITGB5
CUI: C0871470
Disease:
Systolic Pressure 		C 0.700 GeneticVariation GWASCAT Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation. 27841878 2017
dbSNP: rs4141663
rs4141663
Entrez Id: 3693
Gene Symbol: ITGB5
ITGB5
CUI: C0428883
Disease:
Diastolic blood pressure 		C 0.700 GeneticVariation GWASCAT Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation. 27841878 2017
dbSNP: rs7373878
rs7373878
Entrez Id: 3693
Gene Symbol: ITGB5
ITGB5
CUI: C1269683
Disease:
Major Depressive Disorder 		0.700 GeneticVariation GWASDB Dissecting the genetic heterogeneity of depression through age at onset. 22915352 2012
dbSNP: rs2675
rs2675
Entrez Id: 3693
Gene Symbol: ITGB5
ITGB5
CUI: C0027651
Disease:
Neoplasms 		0.010 GeneticVariation BEFREE In addition, genotype AA of rs2675 and genotype GG of rs17664 were associated with a lower chance of GC at stage 1b [OR = 0.39 (0.18-0.85), P = 0.009; and OR = 0.37 (0.17-0.78), P = 0.004, respectively]; also, the frequency of allele G of rs17664 was associated with a lower chance of stage 1b tumor [OR = 0.50 (0.26-0.95), P = 0.021]. 25472585 2015
dbSNP: rs2675
rs2675
Entrez Id: 3693
Gene Symbol: ITGB5
ITGB5
CUI: C0024232
Disease:
Lymphatic Metastasis 		0.010 GeneticVariation BEFREE Our data suggest that polymorphisms of the microRNA-binding sites in the 3' UTR region of integrin are associated with GC susceptibility (rs2675), tumor stage (rs2675, rs17664, and rs3809865), and lymphatic metastasis (rs17664) in Chinese Han population. 25472585 2015
dbSNP: rs2675
rs2675
Entrez Id: 3693
Gene Symbol: ITGB5
ITGB5
CUI: C0024623
Disease:
Malignant neoplasm of stomach 		0.010 GeneticVariation BEFREE Our data suggest that polymorphisms of the microRNA-binding sites in the 3' UTR region of integrin are associated with GC susceptibility (rs2675), tumor stage (rs2675, rs17664, and rs3809865), and lymphatic metastasis (rs17664) in Chinese Han population. 25472585 2015
dbSNP: rs2675
rs2675
Entrez Id: 3693
Gene Symbol: ITGB5
ITGB5
CUI: C0699791
Disease:
Stomach Carcinoma 		0.010 GeneticVariation BEFREE Our data suggest that polymorphisms of the microRNA-binding sites in the 3' UTR region of integrin are associated with GC susceptibility (rs2675), tumor stage (rs2675, rs17664, and rs3809865), and lymphatic metastasis (rs17664) in Chinese Han population. 25472585 2015