ITPA, inosine triphosphatase, 3704

N. diseases: 77; N. variants: 13
Disease: Fibrosis, Liver ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1127354
rs1127354
Entrez Id: 3704
Gene Symbol: ITPA
ITPA
CUI: C0239946
Disease:
Fibrosis, Liver 		0.010 GeneticVariation BEFREE Multivariate analysis showed that IPTA rs1127354 non-genotype CC, HCV genotype, a baseline HCV RNA level <4 × 10 IU/mL, IL-28B rs12979860 genotype CC, and low liver fibrosis were independent predictors for SVR during the combination therapy.IPTA rs1127354 variants and related ITPase were not only related with ribavirin-induced hemolytic anemia but also directly affected the SVR to PEG-IFN plus ribavirin combination therapy in Chinese HCV-infected patients. 28723780 2017