FLG2, filaggrin family member 2, 388698

N. diseases: 14; N. variants: 4
Disease: Dermatitis, Atopic ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12568784
rs12568784
Entrez Id: 339400;388698
Gene Symbol: FLG-AS1;FLG2
FLG-AS1;FLG2
CUI: C0011615
Disease:
Dermatitis, Atopic 		0.010 GeneticVariation BEFREE We noted that patients with S2377X (odds ratio [OR], 0.44; 95% CI, 0.25-0.46) and H1249R (OR, 0.23; 05% CI, 0.12-0.46) were significantly less likely to be free of symptoms of AD, and Q2053del224 (OR, 0.54; 95% CI, 0.16-1.80) trended toward this outcome. 24184149 2014
dbSNP: rs16833974
rs16833974
Entrez Id: 339400;388698
Gene Symbol: FLG-AS1;FLG2
FLG-AS1;FLG2
CUI: C0011615
Disease:
Dermatitis, Atopic 		0.010 GeneticVariation BEFREE We noted that patients with S2377X (odds ratio [OR], 0.44; 95% CI, 0.25-0.46) and H1249R (OR, 0.23; 05% CI, 0.12-0.46) were significantly less likely to be free of symptoms of AD, and Q2053del224 (OR, 0.54; 95% CI, 0.16-1.80) trended toward this outcome. 24184149 2014