rs4925386
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
Colorectal Carcinoma
0.830
GeneticVariation
BEFREE
For SNPs on 18q21 (rs12953717 and rs4464148) and 20q13 (rs4925386 ), alleles that correlate with higher risk for the development of CRC are associated with shorter disease free survival (DFS).
29119627
2018
rs4925386
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
Colorectal Carcinoma
0.830
GeneticVariation
BEFREE
Notably, two independent meta-analyses of genome-wide association studies found the C-allele of LAMA5 rs4925386 -C/T correlated with the risk of colorectal cancer .
26968355
2016
rs4925386
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
Colorectal Carcinoma
C
0.830
GeneticVariation
GWASDB
We identified associations at four new CRC risk loci: 1q41 (rs6691170, odds ratio (OR) = 1.06, P = 9.55 × 10⁻¹⁰ and rs6687758, OR = 1.09, P = 2.27 × 10⁻⁹, 3q26.2 (rs10936599, OR = 0.93, P = 3.39 × 10⁻⁸), 12q13.13 (rs11169552, OR = 0.92, P = 1.89 × 10⁻¹⁰ and rs7136702, OR = 1.06, P = 4.02 × 10⁻⁸) and 20q13.33 (rs4925386 , OR = 0.93, P = 1.89 × 10⁻¹⁰).
20972440
2010
rs4925386
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
Colorectal Carcinoma
C
0.830
GeneticVariation
GWASCAT
We identified associations at four new CRC risk loci: 1q41 (rs6691170, odds ratio (OR) = 1.06, P = 9.55 × 10⁻¹⁰ and rs6687758, OR = 1.09, P = 2.27 × 10⁻⁹, 3q26.2 (rs10936599, OR = 0.93, P = 3.39 × 10⁻⁸), 12q13.13 (rs11169552, OR = 0.92, P = 1.89 × 10⁻¹⁰ and rs7136702, OR = 1.06, P = 4.02 × 10⁻⁸) and 20q13.33 (rs4925386 , OR = 0.93, P = 1.89 × 10⁻¹⁰).
20972440
2010
rs4925386
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
Colorectal Carcinoma
0.830
GeneticVariation
BEFREE
We identified associations at four new CRC risk loci: 1q41 (rs6691170, odds ratio (OR) = 1.06, P = 9.55 × 10⁻¹⁰ and rs6687758, OR = 1.09, P = 2.27 × 10⁻⁹, 3q26.2 (rs10936599, OR = 0.93, P = 3.39 × 10⁻⁸), 12q13.13 (rs11169552, OR = 0.92, P = 1.89 × 10⁻¹⁰ and rs7136702, OR = 1.06, P = 4.02 × 10⁻⁸) and 20q13.33 (rs4925386 , OR = 0.93, P = 1.89 × 10⁻¹⁰).
20972440
2010
rs1741640
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
COLORECTAL CANCER, SUSCEPTIBILITY TO, 3
C
0.700
GeneticVariation
GWASCAT
Association analyses identify 31 new risk loci for colorectal cancer susceptibility.
31089142
2019
rs1741640
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
Malignant tumor of colon
C
0.700
GeneticVariation
GWASCAT
Discovery of common and rare genetic risk variants for colorectal cancer.
30510241
2019
rs1741640
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
COLORECTAL CANCER, SUSCEPTIBILITY TO, 1
C
0.700
GeneticVariation
GWASCAT
Discovery of common and rare genetic risk variants for colorectal cancer.
30510241
2019
rs1741640
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
Malignant neoplasm of large intestine
C
0.700
GeneticVariation
GWASCAT
Discovery of common and rare genetic risk variants for colorectal cancer.
30510241
2019
rs1741640
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
COLORECTAL CANCER, SUSCEPTIBILITY TO, 10
C
0.700
GeneticVariation
GWASCAT
Association analyses identify 31 new risk loci for colorectal cancer susceptibility.
31089142
2019
rs1741640
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
Colorectal Carcinoma
C
0.700
GeneticVariation
GWASCAT
Association analyses identify 31 new risk loci for colorectal cancer susceptibility.
31089142
2019
rs1741640
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
COLORECTAL CANCER, SUSCEPTIBILITY TO, 1
C
0.700
GeneticVariation
GWASCAT
Association analyses identify 31 new risk loci for colorectal cancer susceptibility.
31089142
2019
rs1741640
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
Adenocarcinoma of large intestine
C
0.700
GeneticVariation
GWASCAT
Discovery of common and rare genetic risk variants for colorectal cancer.
30510241
2019
rs1741640
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
Malignant neoplasm of large intestine
C
0.700
GeneticVariation
GWASCAT
Association analyses identify 31 new risk loci for colorectal cancer susceptibility.
31089142
2019
rs1741640
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
Colorectal Neoplasms
C
0.700
GeneticVariation
GWASCAT
Association analyses identify 31 new risk loci for colorectal cancer susceptibility.
31089142
2019
rs1741640
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
Colorectal Carcinoma
C
0.700
GeneticVariation
GWASCAT
Discovery of common and rare genetic risk variants for colorectal cancer.
30510241
2019
rs1741640
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
Colorectal Neoplasms
C
0.700
GeneticVariation
GWASCAT
Discovery of common and rare genetic risk variants for colorectal cancer.
30510241
2019
rs1741640
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
Adenocarcinoma of large intestine
C
0.700
GeneticVariation
GWASCAT
Association analyses identify 31 new risk loci for colorectal cancer susceptibility.
31089142
2019
rs1741640
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
COLORECTAL CANCER, SUSCEPTIBILITY TO, 12
C
0.700
GeneticVariation
GWASCAT
Discovery of common and rare genetic risk variants for colorectal cancer.
30510241
2019
rs1741640
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
Malignant tumor of colon
C
0.700
GeneticVariation
GWASCAT
Association analyses identify 31 new risk loci for colorectal cancer susceptibility.
31089142
2019
rs1741640
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
COLORECTAL CANCER, SUSCEPTIBILITY TO, 10
C
0.700
GeneticVariation
GWASCAT
Discovery of common and rare genetic risk variants for colorectal cancer.
30510241
2019
rs1741640
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
COLORECTAL CANCER, SUSCEPTIBILITY TO, 12
C
0.700
GeneticVariation
GWASCAT
Association analyses identify 31 new risk loci for colorectal cancer susceptibility.
31089142
2019
rs1741640
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
COLORECTAL CANCER, SUSCEPTIBILITY TO, 3
C
0.700
GeneticVariation
GWASCAT
Discovery of common and rare genetic risk variants for colorectal cancer.
30510241
2019
rs1741640
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
Adenoma of large intestine
C
0.700
GeneticVariation
GWASCAT
Discovery of common and rare genetic risk variants for colorectal cancer.
30510241
2019
rs2236521
×
Entrez Id:
3911
Gene Symbol:
LAMA5
LAMA5
Glomerular Filtration Rate
A
0.700
GeneticVariation
GWASCAT
A catalog of genetic loci associated with kidney function from analyses of a million individuals.
31152163
2019