LGALS3, galectin 3, 3958

N. diseases: 557; N. variants: 15
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs76426991
rs76426991
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C2985280
Disease:
Blood Protein Measurement
G 0.700 GeneticVariation GWASCAT Co-regulatory networks of human serum proteins link genetics to disease. 30072576 2018
dbSNP: rs1009977
rs1009977
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0202202
Disease:
Protein measurement
0.700 GeneticVariation GWASDB A genome-wide association study of circulating galectin-3. 23056639 2012
dbSNP: rs1009978
rs1009978
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0202202
Disease:
Protein measurement
0.700 GeneticVariation GWASDB A genome-wide association study of circulating galectin-3. 23056639 2012
dbSNP: rs10498475
rs10498475
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0202202
Disease:
Protein measurement
0.700 GeneticVariation GWASDB A genome-wide association study of circulating galectin-3. 23056639 2012
dbSNP: rs2075601
rs2075601
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0202202
Disease:
Protein measurement
0.700 GeneticVariation GWASDB A genome-wide association study of circulating galectin-3. 23056639 2012
dbSNP: rs2075602
rs2075602
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0202202
Disease:
Protein measurement
0.700 GeneticVariation GWASDB A genome-wide association study of circulating galectin-3. 23056639 2012
dbSNP: rs2075603
rs2075603
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0202202
Disease:
Protein measurement
0.700 GeneticVariation GWASDB A genome-wide association study of circulating galectin-3. 23056639 2012
dbSNP: rs3825613
rs3825613
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0202202
Disease:
Protein measurement
0.700 GeneticVariation GWASDB A genome-wide association study of circulating galectin-3. 23056639 2012
dbSNP: rs4644
rs4644
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0202202
Disease:
Protein measurement
0.700 GeneticVariation GWASDB A genome-wide association study of circulating galectin-3. 23056639 2012
dbSNP: rs4652
rs4652
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0202202
Disease:
Protein measurement
0.700 GeneticVariation GWASDB A genome-wide association study of circulating galectin-3. 23056639 2012
dbSNP: rs8004787
rs8004787
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0202202
Disease:
Protein measurement
0.700 GeneticVariation GWASDB A genome-wide association study of circulating galectin-3. 23056639 2012
dbSNP: rs8013027
rs8013027
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0202202
Disease:
Protein measurement
0.700 GeneticVariation GWASDB A genome-wide association study of circulating galectin-3. 23056639 2012
dbSNP: rs4644
rs4644
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0003873
Disease:
Rheumatoid Arthritis
0.010 GeneticVariation BEFREE Significant association of three SNPs i.e. rs1009977, rs4644, and rs74050921 along with elevated galectin-3 levels were observed with susceptibility towards RA. 31514073 2019
dbSNP: rs4644
rs4644
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0280474
Disease:
Childhood Glioblastoma
0.010 GeneticVariation BEFREE Two SNP sites (rs4644 and rs4652) across the <i>LGALS3</i> gene were associated with increased risk for glioblastoma, and the C allele of rs4652 and the A allele of rs4644 could enhance glioblastoma resistance to radio-chemotherapy, but not cell proliferation. 30341098 2019
dbSNP: rs4644
rs4644
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C1621958
Disease:
Glioblastoma Multiforme
0.010 GeneticVariation BEFREE Two SNP sites (rs4644 and rs4652) across the <i>LGALS3</i> gene were associated with increased risk for glioblastoma, and the C allele of rs4652 and the A allele of rs4644 could enhance glioblastoma resistance to radio-chemotherapy, but not cell proliferation. 30341098 2019
dbSNP: rs4644
rs4644
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0278878
Disease:
Adult Glioblastoma
0.010 GeneticVariation BEFREE Two SNP sites (rs4644 and rs4652) across the <i>LGALS3</i> gene were associated with increased risk for glioblastoma, and the C allele of rs4652 and the A allele of rs4644 could enhance glioblastoma resistance to radio-chemotherapy, but not cell proliferation. 30341098 2019
dbSNP: rs4644
rs4644
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0017636
Disease:
Glioblastoma
0.010 GeneticVariation BEFREE Two SNP sites (rs4644 and rs4652) across the <i>LGALS3</i> gene were associated with increased risk for glioblastoma, and the C allele of rs4652 and the A allele of rs4644 could enhance glioblastoma resistance to radio-chemotherapy, but not cell proliferation. 30341098 2019
dbSNP: rs4652
rs4652
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0280474
Disease:
Childhood Glioblastoma
0.010 GeneticVariation BEFREE Two SNP sites (rs4644 and rs4652) across the <i>LGALS3</i> gene were associated with increased risk for glioblastoma, and the C allele of rs4652 and the A allele of rs4644 could enhance glioblastoma resistance to radio-chemotherapy, but not cell proliferation. 30341098 2019
dbSNP: rs4652
rs4652
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C1621958
Disease:
Glioblastoma Multiforme
0.010 GeneticVariation BEFREE Two SNP sites (rs4644 and rs4652) across the <i>LGALS3</i> gene were associated with increased risk for glioblastoma, and the C allele of rs4652 and the A allele of rs4644 could enhance glioblastoma resistance to radio-chemotherapy, but not cell proliferation. 30341098 2019
dbSNP: rs4652
rs4652
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0278878
Disease:
Adult Glioblastoma
0.010 GeneticVariation BEFREE Two SNP sites (rs4644 and rs4652) across the <i>LGALS3</i> gene were associated with increased risk for glioblastoma, and the C allele of rs4652 and the A allele of rs4644 could enhance glioblastoma resistance to radio-chemotherapy, but not cell proliferation. 30341098 2019
dbSNP: rs4652
rs4652
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0017636
Disease:
Glioblastoma
0.010 GeneticVariation BEFREE Two SNP sites (rs4644 and rs4652) across the <i>LGALS3</i> gene were associated with increased risk for glioblastoma, and the C allele of rs4652 and the A allele of rs4644 could enhance glioblastoma resistance to radio-chemotherapy, but not cell proliferation. 30341098 2019
dbSNP: rs74050921
rs74050921
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0003873
Disease:
Rheumatoid Arthritis
0.010 GeneticVariation BEFREE Significant association of three SNPs i.e. rs1009977, rs4644, and rs74050921 along with elevated galectin-3 levels were observed with susceptibility towards RA. 31514073 2019
dbSNP: rs1009977
rs1009977
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C1449563
Disease:
Cardiomyopathy, Familial Idiopathic
0.010 GeneticVariation BEFREE The frequency of G allelic</span> polymorphism of rs1009977 and the C allelic polymorphism of rs4652 were lower in DCM patients (OR=0.77, 95% CI [0.60-0.99], P=0.045; OR=0.79, 95% CI [0.63-0.99], P=0.042, respectively). 29129812 2018
dbSNP: rs4644
rs4644
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C1449563
Disease:
Cardiomyopathy, Familial Idiopathic
0.010 GeneticVariation BEFREE The A variant of both rs2274273 and rs4644 was associated with lower level of galectin-3 in DCM patients under additive model (P=0.032 for both) and dominant model (P=0.012 for both). 29129812 2018
dbSNP: rs4652
rs4652
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C1449563
Disease:
Cardiomyopathy, Familial Idiopathic
0.010 GeneticVariation BEFREE The frequency of G allelic polymorphism of rs1009977 and the C allelic polymorphism of rs</span>4652 were lower in DCM patients (OR=0.77, 95% CI [0.60-0.99], P=0.045; OR=0.79, 95% CI [0.63-0.99], P=0.042, respectively). 29129812 2018