LIG1, DNA ligase 1, 3978

N. diseases: 30; N. variants: 8
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs780324684
rs780324684
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.700 GeneticVariation UNIPROT
dbSNP: rs780748107
rs780748107
Entrez Id: 3978;107985293
Gene Symbol: LIG1;LOC107985293
LIG1;LOC107985293
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.700 GeneticVariation UNIPROT
dbSNP: rs156641
rs156641
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C0684249
Disease:
Carcinoma of lung 		0.020 GeneticVariation BEFREE The results showed that the rs156641 polymorphism was significantly associated with lung cancer risk (dominant model: OR 0.694, 95 % CI 0.549-0.878; homozygote model: OR 0.677, 95 % CI 0.526-0.871; heterozygote model: OR 0.712, 95 % CI 0.556-0.913; additive model: OR 0.859, 95 % CI 0.767-0.962), whereas no association was found between rs3730931/rs439132/rs20579 polymorphisms and lung cancer. 27352326 2015
dbSNP: rs156641
rs156641
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.020 GeneticVariation BEFREE The results showed that the rs156641 polymorphism was significantly associated with lung cancer risk (dominant model: OR 0.694, 95 % CI 0.549-0.878; homozygote model: OR 0.677, 95 % CI 0.526-0.871; heterozygote model: OR 0.712, 95 % CI 0.556-0.913; additive model: OR 0.859, 95 % CI 0.767-0.962), whereas no association was found between rs3730931/rs439132/rs20579 polymorphisms and lung cancer. 27352326 2015
dbSNP: rs156641
rs156641
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.020 GeneticVariation BEFREE The results showed that the rs156641 polymorphism was significantly associated with lung cancer risk (dominant model: OR 0.694, 95 % CI 0.549-0.878; homozygote model: OR 0.677, 95 % CI 0.526-0.871; heterozygote model: OR 0.712, 95 % CI 0.556-0.913; additive model: OR 0.859, 95 % CI 0.767-0.962), whereas no association was found between rs3730931/rs439132/rs20579 polymorphisms and lung cancer. 27352326 2015
dbSNP: rs20579
rs20579
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.020 GeneticVariation BEFREE The results showed that the rs156641 polymorphism was significantly associated with lung cancer risk (dominant model: OR 0.694, 95 % CI 0.549-0.878; homozygote model: OR 0.677, 95 % CI 0.526-0.871; heterozygote model: OR 0.712, 95 % CI 0.556-0.913; additive model: OR 0.859, 95 % CI 0.767-0.962), whereas no association was found between rs3730931/rs439132/rs20579 polymorphisms and lung cancer. 27352326 2015
dbSNP: rs20579
rs20579
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.020 GeneticVariation BEFREE The results showed that the rs156641 polymorphism was significantly associated with lung cancer risk (dominant model: OR 0.694, 95 % CI 0.549-0.878; homozygote model: OR 0.677, 95 % CI 0.526-0.871; heterozygote model: OR 0.712, 95 % CI 0.556-0.913; additive model: OR 0.859, 95 % CI 0.767-0.962), whereas no association was found between rs3730931/rs439132/rs20579 polymorphisms and lung cancer. 27352326 2015
dbSNP: rs20579
rs20579
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C0684249
Disease:
Carcinoma of lung 		0.020 GeneticVariation BEFREE The results showed that the rs156641 polymorphism was significantly associated with lung cancer risk (dominant model: OR 0.694, 95 % CI 0.549-0.878; homozygote model: OR 0.677, 95 % CI 0.526-0.871; heterozygote model: OR 0.712, 95 % CI 0.556-0.913; additive model: OR 0.859, 95 % CI 0.767-0.962), whereas no association was found between rs3730931/rs439132/rs20579 polymorphisms and lung cancer. 27352326 2015
dbSNP: rs3730931
rs3730931
Entrez Id: 3978;107985293
Gene Symbol: LIG1;LOC107985293
LIG1;LOC107985293
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.020 GeneticVariation BEFREE The results showed that the rs156641 polymorphism was significantly associated with lung cancer risk (dominant model: OR 0.694, 95 % CI 0.549-0.878; homozygote model: OR 0.677, 95 % CI 0.526-0.871; heterozygote model: OR 0.712, 95 % CI 0.556-0.913; additive model: OR 0.859, 95 % CI 0.767-0.962), whereas no association was found between rs3730931/rs439132/rs20579 polymorphisms and lung cancer. 27352326 2015
dbSNP: rs3730931
rs3730931
Entrez Id: 3978;107985293
Gene Symbol: LIG1;LOC107985293
LIG1;LOC107985293
CUI: C0684249
Disease:
Carcinoma of lung 		0.020 GeneticVariation BEFREE The results showed that the rs156641 polymorphism was significantly associated with lung cancer risk (dominant model: OR 0.694, 95 % CI 0.549-0.878; homozygote model: OR 0.677, 95 % CI 0.526-0.871; heterozygote model: OR 0.712, 95 % CI 0.556-0.913; additive model: OR 0.859, 95 % CI 0.767-0.962), whereas no association was found between rs3730931/rs439132/rs20579 polymorphisms and lung cancer. 27352326 2015
dbSNP: rs3730931
rs3730931
Entrez Id: 3978;107985293
Gene Symbol: LIG1;LOC107985293
LIG1;LOC107985293
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.020 GeneticVariation BEFREE The results showed that the rs156641 polymorphism was significantly associated with lung cancer risk (dominant model: OR 0.694, 95 % CI 0.549-0.878; homozygote model: OR 0.677, 95 % CI 0.526-0.871; heterozygote model: OR 0.712, 95 % CI 0.556-0.913; additive model: OR 0.859, 95 % CI 0.767-0.962), whereas no association was found between rs3730931/rs439132/rs20579 polymorphisms and lung cancer. 27352326 2015
dbSNP: rs439132
rs439132
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.020 GeneticVariation BEFREE The results showed that the rs156641 polymorphism was significantly associated with lung cancer risk (dominant model: OR 0.694, 95 % CI 0.549-0.878; homozygote model: OR 0.677, 95 % CI 0.526-0.871; heterozygote model: OR 0.712, 95 % CI 0.556-0.913; additive model: OR 0.859, 95 % CI 0.767-0.962), whereas no association was found between rs3730931/rs439132/rs20579 polymorphisms and lung cancer. 27352326 2015
dbSNP: rs439132
rs439132
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.020 GeneticVariation BEFREE The results showed that the rs156641 polymorphism was significantly associated with lung cancer risk (dominant model: OR 0.694, 95 % CI 0.549-0.878; homozygote model: OR 0.677, 95 % CI 0.526-0.871; heterozygote model: OR 0.712, 95 % CI 0.556-0.913; additive model: OR 0.859, 95 % CI 0.767-0.962), whereas no association was found between rs3730931/rs439132/rs20579 polymorphisms and lung cancer. 27352326 2015
dbSNP: rs439132
rs439132
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C0684249
Disease:
Carcinoma of lung 		0.020 GeneticVariation BEFREE The results showed that the rs156641 polymorphism was significantly associated with lung cancer risk (dominant model: OR 0.694, 95 % CI 0.549-0.878; homozygote model: OR 0.677, 95 % CI 0.526-0.871; heterozygote model: OR 0.712, 95 % CI 0.556-0.913; additive model: OR 0.859, 95 % CI 0.767-0.962), whereas no association was found between rs3730931/rs439132/rs20579 polymorphisms and lung cancer. 27352326 2015
dbSNP: rs156641
rs156641
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C0684249
Disease:
Carcinoma of lung 		0.020 GeneticVariation BEFREE Among African Americans, His/His genotype of ERCC5 His1104Asp (rs17655) was associated with increased lung cancer risk (OR = 1.78; 95% CI: 1.09-2.91), and LIG1 haplotype GGGAA (rs20581, rs156641, rs3730931, rs20579 and rs439132) was associated with reduced lung cancer risk (OR = 0.61; 95% CI: 0.42-0.88). 18709642 2008
dbSNP: rs156641
rs156641
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.020 GeneticVariation BEFREE Among African Americans, His/His genotype of ERCC5 His1104Asp (rs17655) was associated with increased lung cancer risk (OR = 1.78; 95% CI: 1.09-2.91), and LIG1 haplotype GGGAA (rs20581, rs156641, rs3730931, rs20579 and rs439132) was associated with reduced lung cancer risk (OR = 0.61; 95% CI: 0.42-0.88). 18709642 2008
dbSNP: rs156641
rs156641
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.020 GeneticVariation BEFREE Among African Americans, His/His genotype of ERCC5 His1104Asp (rs17655) was associated with increased lung cancer risk (OR = 1.78; 95% CI: 1.09-2.91), and LIG1 haplotype GGGAA (rs20581, rs156641, rs3730931, rs20579 and rs439132) was associated with reduced lung cancer risk (OR = 0.61; 95% CI: 0.42-0.88). 18709642 2008
dbSNP: rs20579
rs20579
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C0684249
Disease:
Carcinoma of lung 		0.020 GeneticVariation BEFREE Among African Americans, His/His genotype of ERCC5 His1104Asp (rs17655) was associated with increased lung cancer risk (OR = 1.78; 95% CI: 1.09-2.91), and LIG1 haplotype GGGAA (rs20581, rs156641, rs3730931, rs20579 and rs439132) was associated with reduced lung cancer risk (OR = 0.61; 95% CI: 0.42-0.88). 18709642 2008
dbSNP: rs20579
rs20579
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.020 GeneticVariation BEFREE Among African Americans, His/His genotype of ERCC5 His1104Asp (rs17655) was associated with increased lung cancer risk (OR = 1.78; 95% CI: 1.09-2.91), and LIG1 haplotype GGGAA (rs20581, rs156641, rs3730931, rs20579 and rs439132) was associated with reduced lung cancer risk (OR = 0.61; 95% CI: 0.42-0.88). 18709642 2008
dbSNP: rs20579
rs20579
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.020 GeneticVariation BEFREE Among African Americans, His/His genotype of ERCC5 His1104Asp (rs17655) was associated with increased lung cancer risk (OR = 1.78; 95% CI: 1.09-2.91), and LIG1 haplotype GGGAA (rs20581, rs156641, rs3730931, rs20579 and rs439132) was associated with reduced lung cancer risk (OR = 0.61; 95% CI: 0.42-0.88). 18709642 2008
dbSNP: rs3730931
rs3730931
Entrez Id: 3978;107985293
Gene Symbol: LIG1;LOC107985293
LIG1;LOC107985293
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.020 GeneticVariation BEFREE Among African Americans, His/His genotype of ERCC5 His1104Asp (rs17655) was associated with increased lung cancer risk (OR = 1.78; 95% CI: 1.09-2.91), and LIG1 haplotype GGGAA (rs20581, rs156641, rs3730931, rs20579 and rs439132) was associated with reduced lung cancer risk (OR = 0.61; 95% CI: 0.42-0.88). 18709642 2008
dbSNP: rs3730931
rs3730931
Entrez Id: 3978;107985293
Gene Symbol: LIG1;LOC107985293
LIG1;LOC107985293
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.020 GeneticVariation BEFREE Among African Americans, His/His genotype of ERCC5 His1104Asp (rs17655) was associated with increased lung cancer risk (OR = 1.78; 95% CI: 1.09-2.91), and LIG1 haplotype GGGAA (rs20581, rs156641, rs3730931, rs20579 and rs439132) was associated with reduced lung cancer risk (OR = 0.61; 95% CI: 0.42-0.88). 18709642 2008
dbSNP: rs3730931
rs3730931
Entrez Id: 3978;107985293
Gene Symbol: LIG1;LOC107985293
LIG1;LOC107985293
CUI: C0684249
Disease:
Carcinoma of lung 		0.020 GeneticVariation BEFREE Among African Americans, His/His genotype of ERCC5 His1104Asp (rs17655) was associated with increased lung cancer risk (OR = 1.78; 95% CI: 1.09-2.91), and LIG1 haplotype GGGAA (rs20581, rs156641, rs3730931, rs20579 and rs439132) was associated with reduced lung cancer risk (OR = 0.61; 95% CI: 0.42-0.88). 18709642 2008
dbSNP: rs439132
rs439132
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.020 GeneticVariation BEFREE Among African Americans, His/His genotype of ERCC5 His1104Asp (rs17655) was associated with increased lung cancer risk (OR = 1.78; 95% CI: 1.09-2.91), and LIG1 haplotype GGGAA (rs20581, rs156641, rs3730931, rs20579 and rs439132) was associated with reduced lung cancer risk (OR = 0.61; 95% CI: 0.42-0.88). 18709642 2008
dbSNP: rs439132
rs439132
Entrez Id: 3978
Gene Symbol: LIG1
LIG1
CUI: C0684249
Disease:
Carcinoma of lung 		0.020 GeneticVariation BEFREE Among African Americans, His/His genotype of ERCC5 His1104Asp (rs17655) was associated with increased lung cancer risk (OR = 1.78; 95% CI: 1.09-2.91), and LIG1 haplotype GGGAA (rs20581, rs156641, rs3730931, rs20579 and rs439132) was associated with reduced lung cancer risk (OR = 0.61; 95% CI: 0.42-0.88). 18709642 2008