LTA, lymphotoxin alpha, 4049

N. diseases: 353; N. variants: 26
Disease: Malignant neoplasm of vulva ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2239704
rs2239704
Entrez Id: 4049;100287329
Gene Symbol: LTA;LOC100287329
LTA;LOC100287329
CUI: C0375071
Disease:
Malignant neoplasm of vulva 		0.010 GeneticVariation BEFREE The rare allele (A) of SNP rs2239704 in the 5' UTR of the LTA gene was significantly associated with increased risks of cervical cancer (OR=1.31, 95% CI: 1.15-1.50; adjusted p-value: 0.013) and vulvar cancer (OR=1.51, 95% CI: 1.30-1.75; adjusted p-value: 1.9 × 10(-5) ). 23824834 2014