MC5R, melanocortin 5 receptor, 4161

N. diseases: 16; N. variants: 3
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1541276
rs1541276
Entrez Id: 4161
Gene Symbol: MC5R
MC5R
CUI: C0028754
Disease:
Obesity
0.010 GeneticVariation BEFREE Weaker associations were detected between the SNPs rs1541276 in the MC5R, rs1926065 in the MC3R genes and obesity (P = 0.04 and P = 0.03, respectively), and between SNPs rs2236700 in the MC5R, rs2118404 in the POMC, rs943003 in the ENPP1 genes and type 2 diabetes (P = 0.03, P = 0.02 and P = 0.02, respectively); these associations did not, however, remain significant after correction for multiple testing. 18551113 2008
dbSNP: rs1541276
rs1541276
Entrez Id: 4161
Gene Symbol: MC5R
MC5R
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.010 GeneticVariation BEFREE Weaker associations were detected between the SNPs rs1541276 in the MC5R, rs1926065 in the MC3R genes and obesity (P = 0.04 and P = 0.03, respectively), and between SNPs rs2236700 in the MC5R, rs2118404 in the POMC, rs943003 in the ENPP1 genes and type 2 diabetes (P = 0.03, P = 0.02 and P = 0.02, respectively); these associations did not, however, remain significant after correction for multiple testing. 18551113 2008
dbSNP: rs2236700
rs2236700
Entrez Id: 4161
Gene Symbol: MC5R
MC5R
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.010 GeneticVariation BEFREE Weaker associations were detected between the SNPs rs1541276 in the MC5R, rs1926065 in the MC3R genes and obesity (P = 0.04 and P = 0.03, respectively), and between SNPs rs2236700 in the MC5R, rs2118404 in the POMC, rs943003 in the ENPP1 genes and type 2 diabetes (P = 0.03, P = 0.02 and P = 0.02, respectively); these associations did not, however, remain significant after correction for multiple testing. 18551113 2008
dbSNP: rs2236700
rs2236700
Entrez Id: 4161
Gene Symbol: MC5R
MC5R
CUI: C0028754
Disease:
Obesity
0.010 GeneticVariation BEFREE Weaker associations were detected between the SNPs rs1541276 in the MC5R, rs1926065 in the MC3R genes and obesity (P = 0.04 and P = 0.03, respectively), and between SNPs rs2236700 in the MC5R, rs2118404 in the POMC, rs943003 in the ENPP1 genes and type 2 diabetes (P = 0.03, P = 0.02 and P = 0.02, respectively); these associations did not, however, remain significant after correction for multiple testing. 18551113 2008
dbSNP: rs2236700
rs2236700
Entrez Id: 4161
Gene Symbol: MC5R
MC5R
CUI: C0005586
Disease:
Bipolar Disorder
0.010 GeneticVariation BEFREE We tested the hypothesis that the potential functional variation Phe209Leu confers susceptibility to bipolar disorder in a case-control study. 16314755 2005
dbSNP: rs758921595
rs758921595
Entrez Id: 4161
Gene Symbol: MC5R
MC5R
CUI: C0005586
Disease:
Bipolar Disorder
0.010 GeneticVariation BEFREE We tested the hypothesis that the potential functional variation Phe209Leu confers susceptibility to bipolar disorder in a case-control study. 16314755 2005