MMP2, matrix metallopeptidase 2, 4313

N. diseases: 1021; N. variants: 43
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs243865
rs243865
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
CUI: C0376358
Disease:
Malignant neoplasm of prostate
0.030 GeneticVariation BEFREE Meta-analysis showed no associations between MMP1 rs1799750, MMP2 rs243865, or MMP7 rs11568818 and prostate cancer risk overall. 30464622 2018
dbSNP: rs243865
rs243865
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
CUI: C0376358
Disease:
Malignant neoplasm of prostate
0.030 GeneticVariation BEFREE Our meta-analysis results suggest that <i>MMP2</i> rs243865 polymorphisms are significantly associated with higher risk of prostate cancer. 29069837 2017
dbSNP: rs243865
rs243865
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
CUI: C0376358
Disease:
Malignant neoplasm of prostate
0.030 GeneticVariation BEFREE MMP2 -1306 C > T (rs243865) polymorphism was not significantly related with prostate cancer susceptibility in Iranian men. 27541146 2017
dbSNP: rs11639960
rs11639960
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
CUI: C0376358
Disease:
Malignant neoplasm of prostate
0.010 GeneticVariation BEFREE However, two of these SNPs (rs17301608 and rs11639960) were examined and were not associated with prostate cancer</span> in a recent genome-wide association study using prostate cancer cases and controls from the Prostate, Lung, Colorectal, and Ovary study cohort. 18398039 2008
dbSNP: rs1477017
rs1477017
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
CUI: C0376358
Disease:
Malignant neoplasm of prostate
0.010 GeneticVariation BEFREE In the MMP2 gene, three intronic SNPs, all in linkage disequilibrium, were associated with overall and advanced prostate cancer (for overall prostate cancer, P(trend) = 0.01 for rs1477017, P(trend) = 0.01 for rs17301608, P(trend) = 0.02 for rs11639960). 18398039 2008
dbSNP: rs17301608
rs17301608
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
CUI: C0376358
Disease:
Malignant neoplasm of prostate
0.010 GeneticVariation BEFREE However, two of these SNPs (rs17301608 and rs11639960) were examined and were not associated with prostate cancer</span> in a recent genome-wide association study using prostate cancer cases and controls from the Prostate, Lung, Colorectal, and Ovary study cohort. 18398039 2008