rs1215450873
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
rs1264516058
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
rs1295485913
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
GeneticVariation
CLINVAR
rs1376550081
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
rs137852759
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
Disease-associated MRE11 mutants impact ATM/ATR DNA damage signaling by distinct mechanisms.
23912341
2013
rs137852759
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling.
22863007
2012
rs137852759
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene.
19383352
2008
rs137852759
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder.
10612394
1999
rs137852759
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
Molecular basis of ataxia telangiectasia and related diseases.
16038621
2005
rs137852761
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
hMRE11: genomic structure and a null mutation identified in a transcript protected from nonsense-mediated mRNA decay.
11371508
2001
rs137852761
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
Clinical course of two Italian siblings with ataxia-telangiectasia-like disorder.
23436002
2013
rs137852761
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
Involvement of novel autophosphorylation sites in ATM activation.
16858402
2006
rs137852761
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
MRE11 mutations and impaired ATM-dependent responses in an Italian family with ataxia-telangiectasia-like disorder.
15269180
2004
rs1555018818
MRE11;ANKRD49
Neoplastic Syndromes, Hereditary
A
0.700
GeneticVariation
CLINVAR
rs371077728
MRE11;MIR548L
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
Utilization of multigene panels in hereditary cancer predisposition testing: analysis of more than 2,000 patients.
24763289
2014
rs371077728
MRE11;MIR548L
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
Evaluation of ACMG-Guideline-Based Variant Classification of Cancer Susceptibility and Non-Cancer-Associated Genes in Families Affected by Breast Cancer.
27153395
2016
rs371077728
MRE11;MIR548L
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
Prevalence of mutations in a panel of breast cancer susceptibility genes in BRCA1/2-negative patients with early-onset breast cancer.
25503501
2015
rs587780138
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
GeneticVariation
CLINVAR
Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing.
22006311
2011
rs587780138
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
GeneticVariation
CLINVAR
Rare disruptive mutations and their contribution to the heritable risk of colorectal cancer.
27329137
2016
rs587781384
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
Panel Testing for Familial Breast Cancer: Calibrating the Tension Between Research and Clinical Care.
26786923
2016
rs587782030
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
rs774277300
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
rs779269083
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
rs780001540
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR
rs786203682
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Neoplastic Syndromes, Hereditary
A
0.700
CausalMutation
CLINVAR