Disease: Breast Carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs684507
rs684507
Entrez Id: 4361;54851
Gene Symbol: MRE11;ANKRD49
MRE11;ANKRD49
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE We found that the increased risk of breast cancer is associated with MRE11 variant rs684507 (odds ratio-OR 3.71, 95% confidence interval-CI 1.68-8.18, p value < 0.0001), whereas, RAD50 variant rs28903089 appeared to have protective effect (OR 0.55, CI 0.29-1.02, p value = 0.003). 29368209 2018
dbSNP: rs2155209
rs2155209
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE MRE11A rs2155209 and RAD52 rs7963551 were found to be associated with BC risk (ORadjusted: 1.87; 95 % CI: 1.23-2.86 and ORadjusted: 0.36; 95 % CI: 0.24-0.58). 25566853 2015
dbSNP: rs601341
rs601341
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE Homozygous carriers of the MRE11A rs601341 A allele had an increased risk of breast cancer (OR = 1.36, 95% CI 1.08-1.71, P = 0.009) with P (trend) = 0.0087. 18553220 2009