OPRM1, opioid receptor mu 1, 4988

N. diseases: 370; N. variants: 42
Disease: Mental Depression ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799971
rs1799971
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
CUI: C0011570
Disease:
Mental Depression 		0.030 GeneticVariation BEFREE One gene × gene interaction, 5-HTTLPR variant of the serotonin transporter (SERT/SLC6A4) in combination with μ opioid receptor (OPRM1, rs1799971) was associated with comorbid depression and conduct problems. 26228411 2015
dbSNP: rs1799971
rs1799971
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
CUI: C0011570
Disease:
Mental Depression 		0.030 GeneticVariation BEFREE However, A118G genotype did not moderate the effects of other similarly severe major life events on depression. 25086307 2014
dbSNP: rs1799971
rs1799971
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
CUI: C0011570
Disease:
Mental Depression 		0.030 GeneticVariation BEFREE The data did not support a role for the Asn40Asp polymorphism in anxiety and depression, despite adequate statistical power to detect small effects. 12210283 2002