Disease: Psoriasis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs27524
rs27524
Entrez Id: 831;51752
Gene Symbol: CAST;ERAP1
CAST;ERAP1
CUI: C0033860
Disease:
Psoriasis 		A 0.800 GeneticVariation GWASCAT Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms. 25574825 2015
dbSNP: rs27432
rs27432
Entrez Id: 51752;102724748
Gene Symbol: ERAP1;LOC102724748
ERAP1;LOC102724748
CUI: C0033860
Disease:
Psoriasis 		A 0.800 GeneticVariation GWASCAT Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. 23143594 2012
dbSNP: rs27432
rs27432
Entrez Id: 51752;102724748
Gene Symbol: ERAP1;LOC102724748
ERAP1;LOC102724748
CUI: C0033860
Disease:
Psoriasis 		0.800 GeneticVariation GWASDB Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. 23143594 2012
dbSNP: rs27524
rs27524
Entrez Id: 831;51752
Gene Symbol: CAST;ERAP1
CAST;ERAP1
CUI: C0033860
Disease:
Psoriasis 		A 0.800 GeneticVariation GWASDB A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. 20953190 2010
dbSNP: rs27524
rs27524
Entrez Id: 831;51752
Gene Symbol: CAST;ERAP1
CAST;ERAP1
CUI: C0033860
Disease:
Psoriasis 		A 0.800 GeneticVariation GWASCAT A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. 20953190 2010
dbSNP: rs27044
rs27044
Entrez Id: 51752;102724748
Gene Symbol: ERAP1;LOC102724748
ERAP1;LOC102724748
CUI: C0033860
Disease:
Psoriasis 		0.710 GeneticVariation BEFREE We have investigated the association and possible functional role of non-synonymous SNPs at different exons of ERAP1 (rs26653: Arg127Pro, rs30187: Lys528Arg and rs27044: Gln730Glu) and their interactions with HLA-C∗06 in psoriasis. 28867178 2017
dbSNP: rs27044
rs27044
Entrez Id: 51752;102724748
Gene Symbol: ERAP1;LOC102724748
ERAP1;LOC102724748
CUI: C0033860
Disease:
Psoriasis 		G 0.710 GeneticVariation GWASCAT Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis. 25854761 2015
dbSNP: rs2549803
rs2549803
Entrez Id: 51752
Gene Symbol: ERAP1
ERAP1
CUI: C0033860
Disease:
Psoriasis 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs2910686
rs2910686
Entrez Id: 51752;64167
Gene Symbol: ERAP1;ERAP2
ERAP1;ERAP2
CUI: C0033860
Disease:
Psoriasis 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs469758
rs469758
Entrez Id: 51752;102724748
Gene Symbol: ERAP1;LOC102724748
ERAP1;LOC102724748
CUI: C0033860
Disease:
Psoriasis 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs39841
rs39841
Entrez Id: 51752;102724748
Gene Symbol: ERAP1;LOC102724748
ERAP1;LOC102724748
CUI: C0033860
Disease:
Psoriasis 		0.700 GeneticVariation GWASCAT Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms. 25574825 2015
dbSNP: rs4869313
rs4869313
Entrez Id: 51752;64167
Gene Symbol: ERAP1;ERAP2
ERAP1;ERAP2
CUI: C0033860
Disease:
Psoriasis 		T 0.700 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688 2015
dbSNP: rs2910686
rs2910686
Entrez Id: 51752;64167
Gene Symbol: ERAP1;ERAP2
ERAP1;ERAP2
CUI: C0033860
Disease:
Psoriasis 		C 0.700 GeneticVariation GWASCAT Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. 23143594 2012
dbSNP: rs151823
rs151823
Entrez Id: 51752
Gene Symbol: ERAP1
ERAP1
CUI: C0033860
Disease:
Psoriasis 		0.700 GeneticVariation GWASDB Association analyses identify six new psoriasis susceptibility loci in the Chinese population. 20953187 2010
dbSNP: rs26653
rs26653
Entrez Id: 51752
Gene Symbol: ERAP1
ERAP1
CUI: C0033860
Disease:
Psoriasis 		0.020 GeneticVariation BEFREE Carrying rs26653 C allele considerably decreased the risk of psori</span>asis by 1.5 times. 30008647 2018
dbSNP: rs26653
rs26653
Entrez Id: 51752
Gene Symbol: ERAP1
ERAP1
CUI: C0033860
Disease:
Psoriasis 		0.020 GeneticVariation BEFREE ERAP1 single-nucleotide polymorphism rs26653, which, to our knowledge, has not previously been reported in psoriasis, is nonsynonymous, has suggestive functional consequences, and herein displays strong association with disease. 22931917 2013
dbSNP: rs30187
rs30187
Entrez Id: 51752
Gene Symbol: ERAP1
ERAP1
CUI: C0033860
Disease:
Psoriasis 		0.010 GeneticVariation BEFREE We have investigated the association and possible functional role of non-synonymous SNPs at different exons of ERAP1 (rs26653: Arg127Pro, rs30187: Lys528Arg and rs27044: Gln730Glu) and their interactions with HLA-C∗06 in psoriasis. 28867178 2017