XRN1, 5'-3' exoribonuclease 1, 54464

N. diseases: 23; N. variants: 14
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs112828099
rs112828099
Entrez Id: 54464
Gene Symbol: XRN1
XRN1
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs146380793
rs146380793
Entrez Id: 54464
Gene Symbol: XRN1
XRN1
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs2306700
rs2306700
Entrez Id: 54464
Gene Symbol: XRN1
XRN1
CUI: C0005612
Disease:
Birth Weight 		T 0.700 GeneticVariation GWASCAT Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. 31043758 2019
dbSNP: rs13061823
rs13061823
Entrez Id: 54464
Gene Symbol: XRN1
XRN1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean 		0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs2862745
rs2862745
Entrez Id: 54464
Gene Symbol: XRN1
XRN1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean 		0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs3816805
rs3816805
Entrez Id: 54464
Gene Symbol: XRN1
XRN1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean 		0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs4441672
rs4441672
Entrez Id: 54464
Gene Symbol: XRN1
XRN1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean 		0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs6440078
rs6440078
Entrez Id: 54464
Gene Symbol: XRN1
XRN1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean 		0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs6440082
rs6440082
Entrez Id: 54464
Gene Symbol: XRN1
XRN1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean 		0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs6802631
rs6802631
Entrez Id: 54464
Gene Symbol: XRN1
XRN1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean 		0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs7652687
rs7652687
Entrez Id: 54464
Gene Symbol: XRN1
XRN1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean 		0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs9289647
rs9289647
Entrez Id: 54464
Gene Symbol: XRN1
XRN1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean 		0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs9821271
rs9821271
Entrez Id: 54464
Gene Symbol: XRN1
XRN1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean 		0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs1802904
rs1802904
Entrez Id: 545;54464
Gene Symbol: ATR;XRN1
ATR;XRN1
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.010 GeneticVariation BEFREE However, meta-analysis of published data revealed a weak association between the ATR SNP rs1802904 (minor allele frequency is 12%) and breast cancer risk, with a summary odds ratio (confidence interval) of 0.90 (0.83-0.98) [p=0.0185] for the minor allele. 23844225 2013
dbSNP: rs1802904
rs1802904
Entrez Id: 545;54464
Gene Symbol: ATR;XRN1
ATR;XRN1
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE However, meta-analysis of published data revealed a weak association between the ATR SNP rs1802904 (minor allele frequency is 12%) and breast cancer risk, with a summary odds ratio (confidence interval) of 0.90 (0.83-0.98) [p=0.0185] for the minor allele. 23844225 2013