Disease: Malignant neoplasm of liver ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs386656364
rs386656364
Entrez Id: 54575;54576;54577;54600
Gene Symbol: UGT1A10;UGT1A8;UGT1A7;UGT1A9
UGT1A10;UGT1A8;UGT1A7;UGT1A9
CUI: C0345904
Disease:
Malignant neoplasm of liver 		0.010 GeneticVariation BEFREE UGT1A7 polymorphisms were present in 93.2% of hepatocellular cancer patients, 74.5% carried the UGT1A7*3 allele (P < 0.001; OR, 10.76; 95% CI, 4.75-24.38), which combines the W208R, N129K, and R131K mutations and encodes a protein with low carcinogen detoxification activity.No UGT1A9 polymorphisms were detected. 11677206 2001
dbSNP: rs771314938
rs771314938
Entrez Id: 54575;54576;54577;54600
Gene Symbol: UGT1A10;UGT1A8;UGT1A7;UGT1A9
UGT1A10;UGT1A8;UGT1A7;UGT1A9
CUI: C0345904
Disease:
Malignant neoplasm of liver 		0.010 GeneticVariation BEFREE UGT1A7 polymorphisms were present in 93.2% of hepatocellular cancer patients, 74.5% carried the UGT1A7*3 allele (P < 0.001; OR, 10.76; 95% CI, 4.75-24.38), which combines the W208R, N129K, and R131K mutations and encodes a protein with low carcinogen detoxification activity.No UGT1A9 polymorphisms were detected. 11677206 2001
dbSNP: rs879625015
rs879625015
Entrez Id: 54575;54576;54577;54600
Gene Symbol: UGT1A10;UGT1A8;UGT1A7;UGT1A9
UGT1A10;UGT1A8;UGT1A7;UGT1A9
CUI: C0345904
Disease:
Malignant neoplasm of liver 		0.010 GeneticVariation BEFREE UGT1A7 polymorphisms were present in 93.2% of hepatocellular cancer patients, 74.5% carried the UGT1A7*3 allele (P < 0.001; OR, 10.76; 95% CI, 4.75-24.38), which combines the W208R, N129K, and R131K mutations and encodes a protein with low carcinogen detoxification activity.No UGT1A9 polymorphisms were detected. 11677206 2001