PPIA, peptidylprolyl isomerase A, 5478

N. diseases: 180; N. variants: 3
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4720485
rs4720485
Entrez Id: 5478;105375259
Gene Symbol: PPIA;LOC105375259
PPIA;LOC105375259
CUI: C0021704
Disease:
Intelligence
A 0.700 GeneticVariation GWASCAT Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. 29942086 2018
dbSNP: rs185203327
rs185203327
Entrez Id: 5478
Gene Symbol: PPIA
PPIA
CUI: C1519383
Disease:
Smoking Behaviors
0.700 GeneticVariation GWASCAT Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer. 26053186 2015
dbSNP: rs185203327
rs185203327
Entrez Id: 5478
Gene Symbol: PPIA
PPIA
CUI: C0037369
Disease:
Smoking
0.700 GeneticVariation GWASCAT Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer. 26053186 2015
dbSNP: rs6850
rs6850
Entrez Id: 5478;105375259
Gene Symbol: PPIA;LOC105375259
PPIA;LOC105375259
CUI: C1956346
Disease:
Coronary Artery Disease
0.020 GeneticVariation BEFREE The CyPA platelet surface expression is associated with mortality whereas CyPA PPIA rs6850 is associated with recurrent MI in patients with symptomatic CAD. 31519036 2020
dbSNP: rs6850
rs6850
Entrez Id: 5478;105375259
Gene Symbol: PPIA;LOC105375259
PPIA;LOC105375259
CUI: C1956346
Disease:
Coronary Artery Disease
0.020 GeneticVariation BEFREE Welchs two-sample t test indicated an association of SNP rs6850: A > G, located at the 5' UTR region with increased plasma levels of cyclophilin A in patients with coronary artery disease and with coronary artery disease associated with diabetes. 26702934 2016
dbSNP: rs6850
rs6850
Entrez Id: 5478;105375259
Gene Symbol: PPIA;LOC105375259
PPIA;LOC105375259
CUI: C0027051
Disease:
Myocardial Infarction
0.010 GeneticVariation BEFREE The CyPA platelet surface expression is associated with mortality whereas CyPA PPIA rs6850 is associated with recurrent MI in patients with symptomatic CAD. 31519036 2020
dbSNP: rs6850
rs6850
Entrez Id: 5478;105375259
Gene Symbol: PPIA;LOC105375259
PPIA;LOC105375259
CUI: C0007222
Disease:
Cardiovascular Diseases
0.010 GeneticVariation BEFREE The aim of this study was to investigate possible associations of CyPA platelet surface expression and a clinically relevant CyPA single-nucleotide polymorphism (CyPA PPIA rs6850) with prognosis in patients with symptomatic cardiovascular disease. 31519036 2020
dbSNP: rs6850
rs6850
Entrez Id: 5478;105375259
Gene Symbol: PPIA;LOC105375259
PPIA;LOC105375259
CUI: C0011849
Disease:
Diabetes Mellitus
0.010 GeneticVariation BEFREE Welchs two-sample t test indicated an association of SNP rs6850: A > G, located at the 5' UTR region with increased plasma levels of cyclophilin A in patients with coronary artery disease and with coronary artery disease associated with diabetes. 26702934 2016
dbSNP: rs6850
rs6850
Entrez Id: 5478;105375259
Gene Symbol: PPIA;LOC105375259
PPIA;LOC105375259
CUI: C2363741
Disease:
HIV-1 infection
0.010 GeneticVariation BEFREE These data suggest that rs6850 G enhances HIV-1 replication through upregulation of CypA expression following HIV-1 infection. 27088296 2016
dbSNP: rs6850
rs6850
Entrez Id: 5478;105375259
Gene Symbol: PPIA;LOC105375259
PPIA;LOC105375259
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.010 GeneticVariation BEFREE Our results indicate that the SNP rs6850: A > G is associated with increased risk for elevated plasma levels of cyclophilin A and coronary artery disease in patients with and without type 2 diabetes. 26702934 2016
dbSNP: rs6850
rs6850
Entrez Id: 5478;105375259
Gene Symbol: PPIA;LOC105375259
PPIA;LOC105375259
CUI: C0011847
Disease:
Diabetes
0.010 GeneticVariation BEFREE Welchs two-sample t test indicated an association of SNP rs6850: A > G, located at the 5' UTR region with increased plasma levels of cyclophilin A in patients with coronary artery disease and with coronary artery disease associated with diabetes. 26702934 2016
dbSNP: rs6850
rs6850
Entrez Id: 5478;105375259
Gene Symbol: PPIA;LOC105375259
PPIA;LOC105375259
CUI: C0010054
Disease:
Coronary Arteriosclerosis
0.010 GeneticVariation BEFREE Welchs two-sample t test indicated an association of SNP rs6850: A > G, located at the 5' UTR region with increased plasma levels of cyclophilin A in patients with coronary artery disease and with coronary artery disease associated with diabetes. 26702934 2016
dbSNP: rs6850
rs6850
Entrez Id: 5478;105375259
Gene Symbol: PPIA;LOC105375259
PPIA;LOC105375259
CUI: C0010068
Disease:
Coronary heart disease
0.010 GeneticVariation BEFREE Welchs two-sample t test indicated an association of SNP rs6850: A > G, located at the 5' UTR region with increased plasma levels of cyclophilin A in patients with coronary artery disease and with coronary artery disease associated with diabetes. 26702934 2016