|
rs805297
|
BAG6;APOM
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.010 |
GeneticVariation |
BEFREE |
Interestingly, the C allele of rs805297 was significantly associated with T2D duration of longer than 10 years (OR = 1.245, p = 0.015).
|
21390319 |
2011 |
|
rs805297
|
BAG6;APOM
|
Rheumatoid Arthritis
|
A |
0.820 |
GeneticVariation |
GWASCAT |
Common variants at the promoter region of the APOM confer a risk of rheumatoid arthritis.
|
21844665 |
2011 |
|
rs805297
|
BAG6;APOM
|
Rheumatoid Arthritis
|
|
0.820 |
GeneticVariation |
BEFREE |
Through GWAS, we identified a novel SNP associated with RA at the APOM gene in the MHC class III region on 6p21.33 (rs805297, odds ratio (OR) = 2.28, P = 5.20 × 10-7).
|
21844665 |
2011 |
|
rs805297
|
BAG6;APOM
|
Rheumatoid Arthritis
|
A |
0.820 |
GeneticVariation |
GWASDB |
Common variants at the promoter region of the APOM confer a risk of rheumatoid arthritis.
|
21844665 |
2011 |
|
rs3117582
|
BAG6;APOM
|
Malignant neoplasm of lung
|
|
0.760 |
GeneticVariation |
GWASDB |
Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls.
|
22899653 |
2012 |
|
rs3117583
|
BAG6;APOM
|
Epstein-Barr Virus Infections
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1).
|
23326239 |
2013 |
|
rs805297
|
BAG6;APOM
|
Rheumatoid Arthritis
|
|
0.820 |
GeneticVariation |
BEFREE |
These findings suggest that the functional single-nucleotide polymorphism APOM rs805297 G/T variant allele was associated with RA risk.
|
23660425 |
2014 |
|
rs3117582
|
BAG6;APOM
|
Carcinoma of lung
|
|
0.760 |
GeneticVariation |
BEFREE |
This meta-analysis demonstrated that the three common variations (rs4324798, rs3117582, and rs9295740) on 6p21 are risk factors associated with increased lung cancer susceptibility, but these associations vary in different ethnic populations.
|
23959479 |
2014 |
|
rs3117582
|
BAG6;APOM
|
Malignant neoplasm of lung
|
|
0.760 |
GeneticVariation |
BEFREE |
This meta-analysis demonstrated that the three common variations (rs4324798, rs3117582, and rs9295740) on 6p21 are risk factors associated with increased lung cancer susceptibility, but these associations vary in different ethnic populations.
|
23959479 |
2014 |
|
rs3117582
|
BAG6;APOM
|
Primary malignant neoplasm of lung
|
|
0.060 |
GeneticVariation |
BEFREE |
This meta-analysis demonstrated that the three common variations (rs4324798, rs3117582, and rs9295740) on 6p21 are risk factors associated with increased lung cancer susceptibility, but these associations vary in different ethnic populations.
|
23959479 |
2014 |
|
rs805296
|
BAG6;APOM
|
Coronary Artery Disease
|
|
0.020 |
GeneticVariation |
BEFREE |
It has been reported that rs940494 and rs805296 SNPs of apolipoprotein M (apoM) gene may confer the risk in the development of type 2 diabetes (T2D) and coronary artery disease (CAD) in the Han Chinese.
|
24341666 |
2013 |
|
rs805296
|
BAG6;APOM
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.010 |
GeneticVariation |
BEFREE |
It has been reported that rs940494 and rs805296 SNPs of apolipoprotein M (apoM) gene may confer the risk in the development of type 2 diabetes (T2D) and coronary artery disease (CAD) in the Han Chinese.
|
24341666 |
2013 |
|
rs805297
|
BAG6;APOM
|
Coronary Artery Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
The results presented here suggest that the rs805297 SNP is not associated with an increased risk of developing CAD, although it does independently correlate with dyslipidaemia in Han Chinese individuals.
|
24341666 |
2013 |
|
rs805297
|
BAG6;APOM
|
Dyslipidemias
|
|
0.010 |
GeneticVariation |
BEFREE |
The results presented here suggest that the rs805297 SNP is not associated with an increased risk of developing CAD, although it does independently correlate with dyslipidaemia in Han Chinese individuals.
|
24341666 |
2013 |
|
rs3117582
|
BAG6;APOM
|
Tuberculosis
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of variable number of tandem repeats in the coding region of the FAM46A gene, FAM46A rs11040 SNP and BAG6 rs3117582 SNP with susceptibility to tuberculosis.
|
24625963 |
2014 |
|
rs3117582
|
BAG6;APOM
|
Lupus Erythematosus, Systemic
|
G |
0.700 |
GeneticVariation |
GWASDB |
GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.
|
24871463 |
2014 |
|
rs3117582
|
BAG6;APOM
|
Malignant neoplasm of lung
|
|
0.760 |
GeneticVariation |
BEFREE |
Furthermore, BAT3 rs3117582 increased lung cancer risk (OR = 1.31, 95 % CI, 1.26-1.35, P < 0.00001).
|
24989925 |
2014 |
|
rs3117582
|
BAG6;APOM
|
Carcinoma of lung
|
|
0.760 |
GeneticVariation |
BEFREE |
Furthermore, BAT3 rs3117582 increased lung cancer risk (OR = 1.31, 95 % CI, 1.26-1.35, P < 0.00001).
|
24989925 |
2014 |
|
rs3117582
|
BAG6;APOM
|
Primary malignant neoplasm of lung
|
|
0.060 |
GeneticVariation |
BEFREE |
Furthermore, BAT3 rs3117582 increased lung cancer risk (OR = 1.31, 95 % CI, 1.26-1.35, P < 0.00001).
|
24989925 |
2014 |
|
rs3117582
|
BAG6;APOM
|
Degenerative polyarthritis
|
|
0.010 |
GeneticVariation |
BEFREE |
Family with sequence similarity 46, member A (FAM46A) gene VNTR and BCL2-Associated Athanogene 6 (BAG6) gene rs3117582 polymorphisms were genotyped in a case-control study with 474 large-joint (hip and knee) osteoarthritis (OA) patients and 568 controls in Croatian population by candidate-gene approach for association with OA.
|
25231575 |
2015 |
|
rs3117582
|
BAG6;APOM
|
Osteoarthritis, Knee
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that BAG6 rs3117582 SNP genotypes were associated with protection (major allele homozygote) and susceptibility (major-minor allele heterozygote) to OA.
|
25231575 |
2015 |
|
rs3117582
|
BAG6;APOM
|
Osteoarthritis of hip
|
|
0.010 |
GeneticVariation |
BEFREE |
Susceptibility to large-joint osteoarthritis (hip and knee) is associated with BAG6 rs3117582 SNP and the VNTR polymorphism in the second exon of the FAM46A gene on chromosome 6.
|
25231575 |
2015 |
|
rs3117582
|
BAG6;APOM
|
Malignant neoplasm of lung
|
|
0.760 |
GeneticVariation |
BEFREE |
We found also that BAG6 rs3117582 SNP was associated with non small cell lung cancer in the Norwegian subjects and the combined Croatian-Norwegian subjects corroborating the earlier finding that BAG6 rs3117582 SNP was associated with lung cancer in Europeans.
|
25884493 |
2015 |
|
rs3117582
|
BAG6;APOM
|
Carcinoma of lung
|
|
0.760 |
GeneticVariation |
BEFREE |
We found also that BAG6 rs3117582 SNP was associated with non small cell lung cancer in the Norwegian subjects and the combined Croatian-Norwegian subjects corroborating the earlier finding that BAG6 rs3117582 SNP was associated with lung cancer in Europeans.
|
25884493 |
2015 |
|
rs3117582
|
BAG6;APOM
|
Primary malignant neoplasm of lung
|
|
0.060 |
GeneticVariation |
BEFREE |
We found also that BAG6 rs3117582 SNP was associated with non small cell lung cancer in the Norwegian subjects and the combined Croatian-Norwegian subjects corroborating the earlier finding that BAG6 rs3117582 SNP was associated with lung cancer in Europeans.
|
25884493 |
2015 |