APOM, apolipoprotein M, 55937

N. diseases: 82; N. variants: 10
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs805297
rs805297
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.820 GeneticVariation BEFREE These findings suggest that the functional single-nucleotide polymorphism APOM rs805297 G/T variant allele was associated with RA risk. 23660425 2014
dbSNP: rs805297
rs805297
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0003873
Disease:
Rheumatoid Arthritis 		A 0.820 GeneticVariation GWASCAT Common variants at the promoter region of the APOM confer a risk of rheumatoid arthritis. 21844665 2011
dbSNP: rs805297
rs805297
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.820 GeneticVariation BEFREE Through GWAS, we identified a novel SNP associated with RA at the APOM gene in the MHC class III region on 6p21.33 (rs805297, odds ratio (OR) = 2.28, P = 5.20 × 10-7). 21844665 2011
dbSNP: rs805297
rs805297
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0003873
Disease:
Rheumatoid Arthritis 		A 0.820 GeneticVariation GWASDB Common variants at the promoter region of the APOM confer a risk of rheumatoid arthritis. 21844665 2011
dbSNP: rs805297
rs805297
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.820 GeneticVariation GWASDB A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. 21156761 2011
dbSNP: rs3117582
rs3117582
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0152013
Disease:
Adenocarcinoma of lung (disorder) 		C 0.800 GeneticVariation GWASCAT A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. 19836008 2009
dbSNP: rs3117582
rs3117582
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0152013
Disease:
Adenocarcinoma of lung (disorder) 		C 0.800 GeneticVariation GWASDB A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. 19836008 2009
dbSNP: rs3117582
rs3117582
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0684249
Disease:
Carcinoma of lung 		0.760 GeneticVariation BEFREE As a result, 15 SNPs on or near 12 genes and one miRNA with strong evidence of association with lung cancer risk were identified, including TERT (rs2736098), CHRNA3 (rs1051730), AGPHD1 (rs8034191), CLPTM1L (rs401681 and rs402710), BAT3 (rs3117582), TRNAA (rs4324798), ERCC2 (Lys751Gln), miR-146a2 (rs2910164), CYP1B1 (Arg48Gly), GSTM1 (null/present), SOD2 (C47T), IL-10 (-592C/A and -819C/T), and TP53 (intron 6). 29110844 2017
dbSNP: rs3117582
rs3117582
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.760 GeneticVariation BEFREE As a result, 15 SNPs on or near 12 genes and one miRNA with strong evidence of association with lung cancer risk were identified, including TERT (rs2736098), CHRNA3 (rs1051730), AGPHD1 (rs8034191), CLPTM1L (rs401681 and rs402710), BAT3 (rs3117582), TRNAA (rs4324798), ERCC2 (Lys751Gln), miR-146a2 (rs2910164), CYP1B1 (Arg48Gly), GSTM1 (null/present), SOD2 (C47T), IL-10 (-592C/A and -819C/T), and TP53 (intron 6). 29110844 2017
dbSNP: rs3117582
rs3117582
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.760 GeneticVariation BEFREE We found also that BAG6 rs3117582 SNP was associated with non small cell lung cancer in the Norwegian subjects and the combined Croatian-Norwegian subjects corroborating the earlier finding that BAG6 rs3117582 SNP was associated with lung cancer in Europeans. 25884493 2015
dbSNP: rs3117582
rs3117582
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0684249
Disease:
Carcinoma of lung 		0.760 GeneticVariation BEFREE We found also that BAG6 rs3117582 SNP was associated with non small cell lung cancer in the Norwegian subjects and the combined Croatian-Norwegian subjects corroborating the earlier finding that BAG6 rs3117582 SNP was associated with lung cancer in Europeans. 25884493 2015
dbSNP: rs3117582
rs3117582
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0684249
Disease:
Carcinoma of lung 		0.760 GeneticVariation BEFREE This meta-analysis demonstrated that the three common variations (rs4324798, rs3117582, and rs9295740) on 6p21 are risk factors associated with increased lung cancer susceptibility, but these associations vary in different ethnic populations. 23959479 2014
dbSNP: rs3117582
rs3117582
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.760 GeneticVariation BEFREE Furthermore, BAT3 rs3117582 increased lung cancer risk (OR = 1.31, 95 % CI, 1.26-1.35, P < 0.00001). 24989925 2014
dbSNP: rs3117582
rs3117582
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0684249
Disease:
Carcinoma of lung 		0.760 GeneticVariation BEFREE Furthermore, BAT3 rs3117582 increased lung cancer risk (OR = 1.31, 95 % CI, 1.26-1.35, P < 0.00001). 24989925 2014
dbSNP: rs3117582
rs3117582
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.760 GeneticVariation BEFREE This meta-analysis demonstrated that the three common variations (rs4324798, rs3117582, and rs9295740) on 6p21 are risk factors associated with increased lung cancer susceptibility, but these associations vary in different ethnic populations. 23959479 2014
dbSNP: rs3117582
rs3117582
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.760 GeneticVariation GWASDB Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. 22899653 2012
dbSNP: rs3117582
rs3117582
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.760 GeneticVariation BEFREE SNP rs31489 showed the strongest evidence of familial lung cancer association on 5p15.33 (P = 2 x 10(-4); odds ratio, 0.57; 95% confidence interval, 0.42-0.77), whereas rs3117582 showed a weak association on 6p21.33 (P = 0.09; odds ratio, 1.47; 95% confidence interval, 0.94-2.31). 20142248 2010
dbSNP: rs3117582
rs3117582
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0684249
Disease:
Carcinoma of lung 		0.760 GeneticVariation BEFREE SNP rs31489 showed the strongest evidence of familial lung cancer association on 5p15.33 (P = 2 x 10(-4); odds ratio, 0.57; 95% confidence interval, 0.42-0.77), whereas rs3117582 showed a weak association on 6p21.33 (P = 0.09; odds ratio, 1.47; 95% confidence interval, 0.94-2.31). 20142248 2010
dbSNP: rs3117582
rs3117582
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0684249
Disease:
Carcinoma of lung 		0.760 GeneticVariation GWASCAT A meta-analysis provided increased support that variation at 15q25.1 (rs8034191; P = 3.24 x 10(-26)), 5p15.33 (rs4975616; P = 2.99 x 10(-9)), and 6p21.33 (rs3117582; P = 4.46 x 10(-10)) influences lung cancer risk. 19654303 2009
dbSNP: rs3117582
rs3117582
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.760 GeneticVariation BEFREE A meta-analysis provided increased support that variation at 15q25.1 (rs8034191; P = 3.24 x 10(-26)), 5p15.33 (rs4975616; P = 2.99 x 10(-9)), and 6p21.33 (rs3117582; P = 4.46 x 10(-10)) influences lung cancer risk. 19654303 2009
dbSNP: rs3117582
rs3117582
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0684249
Disease:
Carcinoma of lung 		0.760 GeneticVariation BEFREE A meta-analysis provided increased support that variation at 15q25.1 (rs8034191; P = 3.24 x 10(-26)), 5p15.33 (rs4975616; P = 2.99 x 10(-9)), and 6p21.33 (rs3117582; P = 4.46 x 10(-10)) influences lung cancer risk. 19654303 2009
dbSNP: rs3117582
rs3117582
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.760 GeneticVariation GWASDB A meta-analysis provided increased support that variation at 15q25.1 (rs8034191; P = 3.24 x 10(-26)), 5p15.33 (rs4975616; P = 2.99 x 10(-9)), and 6p21.33 (rs3117582; P = 4.46 x 10(-10)) influences lung cancer risk. 19654303 2009
dbSNP: rs3117582
rs3117582
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0242379
Disease:
Malignant neoplasm of lung 		C 0.760 GeneticVariation GWASDB Common 5p15.33 and 6p21.33 variants influence lung cancer risk. 18978787 2008
dbSNP: rs3117582
rs3117582
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C0684249
Disease:
Carcinoma of lung 		C 0.760 GeneticVariation GWASCAT Common 5p15.33 and 6p21.33 variants influence lung cancer risk. 18978787 2008
dbSNP: rs1266078
rs1266078
Entrez Id: 7917;55937
Gene Symbol: BAG6;APOM
BAG6;APOM
CUI: C2985280
Disease:
Blood Protein Measurement 		G 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018