PTGER3, prostaglandin E receptor 3, 5733

N. diseases: 82; N. variants: 4
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs573688
rs573688
Entrez Id: 5733;107985517
Gene Symbol: PTGER3;LOC107985517
PTGER3;LOC107985517
CUI: C0021704
Disease:
Intelligence 		T 0.700 GeneticVariation GWASCAT A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence. 29326435 2019
dbSNP: rs875727
rs875727
Entrez Id: 5733
Gene Symbol: PTGER3
PTGER3
CUI: C0017612
Disease:
Glaucoma, Open-Angle 		0.700 GeneticVariation GWASDB A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma. 22419738 2012
dbSNP: rs1409986
rs1409986
Entrez Id: 5733
Gene Symbol: PTGER3
PTGER3
CUI: C0520679
Disease:
Sleep Apnea, Obstructive 		0.010 GeneticVariation BEFREE Among 2,904 individuals of European ancestry, rs1409986 in the prostaglandin E2 receptor (PTGER3) gene was significantly associated with OSA. 23155414 2012
dbSNP: rs1409986
rs1409986
Entrez Id: 5733
Gene Symbol: PTGER3
PTGER3
CUI: C0003578
Disease:
Apnea 		0.010 GeneticVariation BEFREE Consistency of effects between rs7030789 and rs1409986 in LPAR1 and PTGER3 and apnea phenotypes were observed in independent clinic-based cohorts.Novel genetic loci for apnea phenotypes were identified through the use of customized gene chips and meta-analyses of cohort data with replication in clinic-based samples. 23155414 2012
dbSNP: rs11209716
rs11209716
Entrez Id: 5733
Gene Symbol: PTGER3
PTGER3
CUI: C0010200
Disease:
Coughing 		0.010 GeneticVariation BEFREE We found that genetic polymorphisms in MME [rs2016848, P=0.002, odds ratio (OR)=1.795], BDKRB2 (rs8012552, P=0.012, OR=1.609), PTGER3 (rs11209716, P=0.002, OR=0.565), and ACE (rs4344) genes are associated with ACEi-related cough. 21052031 2011