|
rs11191438
|
AS3MT;BORCS7-ASMT
|
Carcinoma of bladder
|
|
0.010 |
GeneticVariation |
BEFREE |
AS3MT rs11191438 (C > G) G/G genotype, AS3MT rs10748835 (A > G) G/G genotype, and AS3MT rs1046778 (C > T) T/T genotype were found to be related to BC risk, where the odds ratio (OR) (95% CI) was 0.50 (0.31-0.82), 0.49 (0.30-0.79), and 0.54 (0.36-0.80), respectively.
|
29669044 |
2018 |
|
rs11191438
|
AS3MT;BORCS7-ASMT
|
Malignant neoplasm of urinary bladder
|
|
0.010 |
GeneticVariation |
BEFREE |
AS3MT rs11191438 (C > G) G/G genotype, AS3MT rs10748835 (A > G) G/G genotype, and AS3MT rs1046778 (C > T) T/T genotype were found to be related to BC risk, where the odds ratio (OR) (95% CI) was 0.50 (0.31-0.82), 0.49 (0.30-0.79), and 0.54 (0.36-0.80), respectively.
|
29669044 |
2018 |
|
rs11191438
|
AS3MT;BORCS7-ASMT
|
Bladder Neoplasm
|
|
0.010 |
GeneticVariation |
BEFREE |
AS3MT rs11191438 (C > G) G/G genotype, AS3MT rs10748835 (A > G) G/G genotype, and AS3MT rs1046778 (C > T) T/T genotype were found to be related to BC risk, where the odds ratio (OR) (95% CI) was 0.50 (0.31-0.82), 0.49 (0.30-0.79), and 0.54 (0.36-0.80), respectively.
|
29669044 |
2018 |
|
rs12244388
|
AS3MT;BORCS7-ASMT
|
Schizophrenia
|
|
0.700 |
GeneticVariation |
GWASCAT |
Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study.
|
31268507 |
2019 |
|
rs1046778
|
AS3MT;BORCS7-ASMT;LOC107984265
|
Schizophrenia
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variants at VRK2 and TCF4 conferring risk of schizophrenia.
|
21791550 |
2011 |
|
rs10883795
|
AS3MT;BORCS7-ASMT
|
Schizophrenia
|
|
0.700 |
GeneticVariation |
GWASCAT |
Common variants on 2p16.1, 6p22.1 and 10q24.32 are associated with schizophrenia in Han Chinese population.
|
27922604 |
2017 |
|
rs3740393
|
AS3MT;BORCS7-ASMT
|
Meningomyelocele
|
|
0.010 |
GeneticVariation |
BEFREE |
Drinking water inorganic arsenic concentration was associated with increased risk of myelomeningocele for participants with 4 of the 14 studied single-nucleotide polymorphisms in genes involved in folate metabolism: the AA/AG genotype of rs2236225 (MTHFD1), the GG genotype of rs1051266 (SLC19A1), the TT genotype of rs7560488 (DNMT3A), and the GG genotype of rs3740393 (AS3MT) with adjusted odds ratio of 1.13, 1.31, 1.20, and 1.25 for rs2236225, rs1051266, rs7560488, and rs3740393, respectively.
|
26250961 |
2015 |
|
rs3740393
|
AS3MT;BORCS7-ASMT
|
Carcinoma of lung
|
|
0.010 |
GeneticVariation |
BEFREE |
For example, compared to wildtypes, individuals carrying minor alleles in AS3MT rs3740393 had lower %MMA (mean difference = -1.9%, 95% CI: -3.3, -0.4), higher %DMA (mean difference = 4.0%, 95% CI: 1.5, 6.5), and lower odds ratios for bladder (OR = 0.3; 95% CI: 0.1-0.6) and lung cancer (OR = 0.6; 95% CI: 0.2-1.1).
|
28640505 |
2017 |
|
rs3740393
|
AS3MT;BORCS7-ASMT
|
Malignant neoplasm of lung
|
|
0.010 |
GeneticVariation |
BEFREE |
For example, compared to wildtypes, individuals carrying minor alleles in AS3MT rs3740393 had lower %MMA (mean difference = -1.9%, 95% CI: -3.3, -0.4), higher %DMA (mean difference = 4.0%, 95% CI: 1.5, 6.5), and lower odds ratios for bladder (OR = 0.3; 95% CI: 0.1-0.6) and lung cancer (OR = 0.6; 95% CI: 0.2-1.1).
|
28640505 |
2017 |
|
rs3740393
|
AS3MT;BORCS7-ASMT
|
Primary malignant neoplasm of lung
|
|
0.010 |
GeneticVariation |
BEFREE |
For example, compared to wildtypes, individuals carrying minor alleles in AS3MT rs3740393 had lower %MMA (mean difference = -1.9%, 95% CI: -3.3, -0.4), higher %DMA (mean difference = 4.0%, 95% CI: 1.5, 6.5), and lower odds ratios for bladder (OR = 0.3; 95% CI: 0.1-0.6) and lung cancer (OR = 0.6; 95% CI: 0.2-1.1).
|
28640505 |
2017 |
|
rs12416687
|
AS3MT;BORCS7-ASMT
|
Mean blood pressure
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia.
|
24954895 |
2014 |
|
rs12416687
|
AS3MT;BORCS7-ASMT
|
Blood Pressure
|
T |
0.700 |
GeneticVariation |
GWASDB |
Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia.
|
24954895 |
2014 |
|
rs7085104
|
AS3MT;BORCS7-ASMT
|
Schizophrenia
|
A |
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
|
23974872 |
2013 |
|
rs7085104
|
AS3MT;BORCS7-ASMT
|
Schizophrenia
|
A |
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
|
23974872 |
2013 |
|
rs7085104
|
AS3MT;BORCS7-ASMT
|
Schizophrenia
|
A |
0.800 |
GeneticVariation |
GWASCAT |
Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.
|
30285260 |
2019 |
|
rs1046778
|
AS3MT;BORCS7-ASMT;LOC107984265
|
Malignant neoplasm of urinary bladder
|
|
0.020 |
GeneticVariation |
BEFREE |
High MMA%, low DMA% and AS3MT rs1046778 C/C + C/T genotype predicted a significantly higher risk of BC according to stepwise multiple logistic regression analyses.
|
29669044 |
2018 |
|
rs1046778
|
AS3MT;BORCS7-ASMT;LOC107984265
|
Carcinoma of bladder
|
|
0.020 |
GeneticVariation |
BEFREE |
High MMA%, low DMA% and AS3MT rs1046778 C/C + C/T genotype predicted a significantly higher risk of BC according to stepwise multiple logistic regression analyses.
|
29669044 |
2018 |
|
rs1046778
|
AS3MT;BORCS7-ASMT;LOC107984265
|
Bladder Neoplasm
|
|
0.020 |
GeneticVariation |
BEFREE |
High MMA%, low DMA% and AS3MT rs1046778 C/C + C/T genotype predicted a significantly higher risk of BC according to stepwise multiple logistic regression analyses.
|
29669044 |
2018 |
|
rs3740390
|
AS3MT;BORCS7-ASMT
|
Coronary Artery Disease
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
|
rs11191454
|
AS3MT;BORCS7-ASMT;LOC107984265
|
Attention deficit hyperactivity disorder
|
|
0.810 |
GeneticVariation |
GWASDB |
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
|
23453885 |
2013 |
|
rs11191454
|
AS3MT;BORCS7-ASMT;LOC107984265
|
Attention deficit hyperactivity disorder
|
|
0.810 |
GeneticVariation |
GWASCAT |
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
|
23453885 |
2013 |
|
rs11191454
|
AS3MT;BORCS7-ASMT;LOC107984265
|
Bipolar Disorder
|
|
0.700 |
GeneticVariation |
GWASCAT |
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
|
23453885 |
2013 |
|
rs11191454
|
AS3MT;BORCS7-ASMT;LOC107984265
|
Child Development Disorders, Pervasive
|
|
0.700 |
GeneticVariation |
GWASCAT |
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
|
23453885 |
2013 |
|
rs11191454
|
AS3MT;BORCS7-ASMT;LOC107984265
|
Major Depressive Disorder
|
|
0.700 |
GeneticVariation |
GWASCAT |
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
|
23453885 |
2013 |
|
rs11191454
|
AS3MT;BORCS7-ASMT;LOC107984265
|
Schizophrenia
|
|
0.700 |
GeneticVariation |
GWASCAT |
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
|
23453885 |
2013 |