Disease: Diabetes Mellitus, Non-Insulin-Dependent ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs16995309
rs16995309
Entrez Id: 5770
Gene Symbol: PTPN1
PTPN1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.020 GeneticVariation BEFREE The Pro387Leu variant of protein tyrosine phosphatase-1B is not associated with diabetes mellitus type 2 in a German population. 15715684 2005
dbSNP: rs16995309
rs16995309
Entrez Id: 5770
Gene Symbol: PTPN1
PTPN1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.020 GeneticVariation BEFREE In summary, a rare P387L variant of the PTP-1B gene is associated with a 3.7 (CI 1.26-10.93, P = 0.02) genotype relative risk of type 2 diabetes in the examined population of Danish Caucasian subjects and results in impaired in vitro serine phosphorylation of the PTP-1B peptide. 11756316 2002
dbSNP: rs16995304
rs16995304
Entrez Id: 5770
Gene Symbol: PTPN1
PTPN1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 GeneticVariation BEFREE The G381S and 3'UTR+104insG insertion variants were not associated with type 2 diabetes. 11756316 2002