SHMT1, serine hydroxymethyltransferase 1, 6470

N. diseases: 106; N. variants: 12
Disease: Breast Carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1979277
rs1979277
Entrez Id: 6470
Gene Symbol: SHMT1
SHMT1
CUI: C0678222
Disease:
Breast Carcinoma 		0.040 GeneticVariation BEFREE Therefore, our meta-analysis suggested that the SHMT1 C1420T polymorphism was associated with decreased risk of breast cancer. 26125758 2015
dbSNP: rs1979277
rs1979277
Entrez Id: 6470
Gene Symbol: SHMT1
SHMT1
CUI: C0678222
Disease:
Breast Carcinoma 		0.040 GeneticVariation BEFREE Our meta-analysis failed to detect association between SH</span>MT1 C1420T polymorphism and breast cancer risk. 24789272 2014
dbSNP: rs1979277
rs1979277
Entrez Id: 6470
Gene Symbol: SHMT1
SHMT1
CUI: C0678222
Disease:
Breast Carcinoma 		0.040 GeneticVariation BEFREE Conversely, for women over 50, the risk of breast cancer development was statistically associated with the MTHFR 677CT genotype, but especially significant was risk associated with the presence of the polymorphic allele of cSHMT C1420T (P = 0.0120) and the protective effect associated with the RFC1 G80A polymorphism allele (P = 0.0021), was restrict to this age group. 22134752 2012
dbSNP: rs1979277
rs1979277
Entrez Id: 6470
Gene Symbol: SHMT1
SHMT1
CUI: C0678222
Disease:
Breast Carcinoma 		0.040 GeneticVariation BEFREE A nested case-control study within the Nurses' Health Study was used to investigate an association between cSHMT (1420C --> T) and breast cancer risk. 19707223 2010