SLIT3, slit guidance ligand 3, 6586

N. diseases: 62; N. variants: 7
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2974438
rs2974438
Entrez Id: 6586
Gene Symbol: SLIT3
SLIT3
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Characterizing rare and low-frequency height-associated variants in the Japanese population. 31562340 2019
dbSNP: rs4282339
rs4282339
Entrez Id: 6586
Gene Symbol: SLIT3
SLIT3
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs76493495
rs76493495
Entrez Id: 6586
Gene Symbol: SLIT3
SLIT3
CUI: C1305855
Disease:
Body mass index 		0.700 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs7735612
rs7735612
Entrez Id: 6586;105377712
Gene Symbol: SLIT3;LOC105377712
SLIT3;LOC105377712
CUI: C2063866
Disease:
Depressive Disorder, Treatment-Resistant 		C 0.700 GeneticVariation GWASCAT Genome-wide association study of treatment-resistance in depression and meta-analysis of three independent samples. 30468137 2019
dbSNP: rs12188351
rs12188351
Entrez Id: 6586
Gene Symbol: SLIT3
SLIT3
CUI: C0004238
Disease:
Atrial Fibrillation 		A 0.700 GeneticVariation GWASCAT Biobank-driven genomic discovery yields new insight into atrial fibrillation biology. 30061737 2018
dbSNP: rs4282339
rs4282339
Entrez Id: 6586
Gene Symbol: SLIT3
SLIT3
CUI: C0005890
Disease:
Body Height 		A 0.700 GeneticVariation GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017
dbSNP: rs12188351
rs12188351
Entrez Id: 6586
Gene Symbol: SLIT3
SLIT3
CUI: C0033860
Disease:
Psoriasis 		0.700 GeneticVariation GWASCAT Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms. 25574825 2015
dbSNP: rs4282339
rs4282339
Entrez Id: 6586
Gene Symbol: SLIT3
SLIT3
CUI: C0005890
Disease:
Body Height 		A 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. 25429064 2015
dbSNP: rs2974438
rs2974438
Entrez Id: 6586
Gene Symbol: SLIT3
SLIT3
CUI: C0005890
Disease:
Body Height 		A 0.700 GeneticVariation GWASCAT Defining the role of common variation in the genomic and biological architecture of adult human height. 25282103 2014
dbSNP: rs4282339
rs4282339
Entrez Id: 6586
Gene Symbol: SLIT3
SLIT3
CUI: C0489786
Disease:
Height 		0.700 GeneticVariation GWASDB Hundreds of variants clustered in genomic loci and biological pathways affect human height. 20881960 2010
dbSNP: rs4282339
rs4282339
Entrez Id: 6586
Gene Symbol: SLIT3
SLIT3
CUI: C0005890
Disease:
Body Height 		A 0.700 GeneticVariation GWASCAT Hundreds of variants clustered in genomic loci and biological pathways affect human height. 20881960 2010
dbSNP: rs11134527
rs11134527
Entrez Id: 6586;407001
Gene Symbol: SLIT3;MIR218-2
SLIT3;MIR218-2
CUI: C0006826
Disease:
Malignant Neoplasms 		0.040 GeneticVariation BEFREE Previous studies have reported that <i>miR-218</i> rs11134527 A>G is associated with susceptibility to various cancer risks. 29717030 2018
dbSNP: rs11134527
rs11134527
Entrez Id: 6586;407001
Gene Symbol: SLIT3;MIR218-2
SLIT3;MIR218-2
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.040 GeneticVariation BEFREE In summary, the findings of this meta-analysis did not support an association between miR-218 rs11134527 polymorphism and cancer risk. 30120974 2018
dbSNP: rs11134527
rs11134527
Entrez Id: 6586;407001
Gene Symbol: SLIT3;MIR218-2
SLIT3;MIR218-2
CUI: C0006826
Disease:
Malignant Neoplasms 		0.040 GeneticVariation BEFREE In summary, the findings of this meta-analysis did not support an association between miR-218 rs11134527 polymorphism and cancer risk. 30120974 2018
dbSNP: rs11134527
rs11134527
Entrez Id: 6586;407001
Gene Symbol: SLIT3;MIR218-2
SLIT3;MIR218-2
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.040 GeneticVariation BEFREE Previous studies have reported that <i>miR-218</i> rs11134527 A>G is associated with susceptibility to various cancer risks. 29717030 2018
dbSNP: rs11134527
rs11134527
Entrez Id: 6586;407001
Gene Symbol: SLIT3;MIR218-2
SLIT3;MIR218-2
CUI: C0302592
Disease:
Cervix carcinoma 		0.040 GeneticVariation BEFREE These results indicated that rs11134527 in pri-miR-218-2 and rs531564 in pri-miR-124-1 could be associated with CIN and cervical cancer in the Chinese Han population. 29152130 2017
dbSNP: rs11134527
rs11134527
Entrez Id: 6586;407001
Gene Symbol: SLIT3;MIR218-2
SLIT3;MIR218-2
CUI: C0006826
Disease:
Malignant Neoplasms 		0.040 GeneticVariation BEFREE Pri-mir-218 rs11134527 and LAMB3 rs2566 were genotyped in ESCC patients and 745 controls to assess their associations with cancer risk and overall survival. 25337271 2014
dbSNP: rs11134527
rs11134527
Entrez Id: 6586;407001
Gene Symbol: SLIT3;MIR218-2
SLIT3;MIR218-2
CUI: C0006826
Disease:
Malignant Neoplasms 		0.040 GeneticVariation BEFREE The findings suggest that pre-miR-218 rs11134527 polymorphism may have some relation to cancer development in Chinese. 24761857 2014
dbSNP: rs11134527
rs11134527
Entrez Id: 6586;407001
Gene Symbol: SLIT3;MIR218-2
SLIT3;MIR218-2
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.040 GeneticVariation BEFREE The findings suggest that pre-miR-218 rs11134527 polymorphism may have some relation to cancer development in Chinese. 24761857 2014
dbSNP: rs11134527
rs11134527
Entrez Id: 6586;407001
Gene Symbol: SLIT3;MIR218-2
SLIT3;MIR218-2
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.040 GeneticVariation BEFREE Pri-mir-218 rs11134527 and LAMB3 rs2566 were genotyped in ESCC patients and 745 controls to assess their associations with cancer risk and overall survival. 25337271 2014
dbSNP: rs11134527
rs11134527
Entrez Id: 6586;407001
Gene Symbol: SLIT3;MIR218-2
SLIT3;MIR218-2
CUI: C0302592
Disease:
Cervix carcinoma 		0.040 GeneticVariation BEFREE MiR-218 plays an important role in heart development in zebrafish. pri-miR-218 rs11134527 variant is associated with cervical cancer carcinogenesis. 23566829 2013
dbSNP: rs11134527
rs11134527
Entrez Id: 6586;407001
Gene Symbol: SLIT3;MIR218-2
SLIT3;MIR218-2
CUI: C0302592
Disease:
Cervix carcinoma 		0.040 GeneticVariation BEFREE The pri-miR-218 rs11134527 SNP was significantly associated with the risk of cervical carcinoma in Eastern Chinese women. 23320911 2013
dbSNP: rs11134527
rs11134527
Entrez Id: 6586;407001
Gene Symbol: SLIT3;MIR218-2
SLIT3;MIR218-2
CUI: C0302592
Disease:
Cervix carcinoma 		0.040 GeneticVariation BEFREE These findings indicate that pri-miR-218 rs11134527 and LAMB3 rs2566 may contribute to cervical cancer carcinogenesis, and further validations in diverse populations and functional characterizations are warranted. 20163849 2010
dbSNP: rs11134527
rs11134527
Entrez Id: 6586;407001
Gene Symbol: SLIT3;MIR218-2
SLIT3;MIR218-2
CUI: C0007847
Disease:
Malignant tumor of cervix 		0.030 GeneticVariation BEFREE These results indicated that rs11134527 in pri-miR-218-2 and rs531564 in pri-miR-124-1 could be associated with CIN and cervical cancer in the Chinese Han population. 29152130 2017
dbSNP: rs11134527
rs11134527
Entrez Id: 6586;407001
Gene Symbol: SLIT3;MIR218-2
SLIT3;MIR218-2
CUI: C4048328
Disease:
cervical cancer 		0.030 GeneticVariation BEFREE These results indicated that rs11134527 in pri-miR-218-2 and rs531564 in pri-miR-124-1 could be associated with CIN and cervical cancer in the Chinese Han population. 29152130 2017