SRD5A2, steroid 5 alpha-reductase 2, 6716

N. diseases: 106; N. variants: 55
Disease: Metastasis from malignant tumor of prostate ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2208532
rs2208532
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
CUI: C1282496
Disease:
Metastasis from malignant tumor of prostate 		0.010 GeneticVariation BEFREE We studied the polymorphisms rs518673 and rs166050 in SRD5A1, and rs12470143, rs523349, rs676033 and rs2208532 in SRD5A2 as well as the time to CRPC progression and overall survival in 104 patients with metastatic prostate cancer that had undergone primary ADT. 26169017 2015
dbSNP: rs523349
rs523349
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
CUI: C1282496
Disease:
Metastasis from malignant tumor of prostate 		0.010 GeneticVariation BEFREE Furthermore, SRD5A2 rs523349 polymorphism may be a promising biomarker for metastatic prostate cancer patients treated with primary ADT and a molecular target for advanced prostate cancer. 26169017 2015
dbSNP: rs676033
rs676033
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
CUI: C1282496
Disease:
Metastasis from malignant tumor of prostate 		0.010 GeneticVariation BEFREE We studied the polymorphisms rs518673 and rs166050 in SRD5A1, and rs12470143, rs523349, rs676033 and rs2208532 in SRD5A2 as well as the time to CRPC progression and overall survival in 104 patients with metastatic prostate cancer that had undergone primary ADT. 26169017 2015