Disease: Diabetes ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1889018
rs1889018
Entrez Id: 6720
Gene Symbol: SREBF1
SREBF1
CUI: C0011847
Disease:
Diabetes 		0.020 GeneticVariation BEFREE The diabetes-associated alleles also associated strongly with a higher plasma glucose at 30 and 120 min and serum insulin at 120 min during an oral glucose tolerance test (all P < 0.006) and the minor allele of rs1889018 with a surrogate measure of insulin sensitivity (P = 0.03). 18192539 2008
dbSNP: rs1889018
rs1889018
Entrez Id: 6720
Gene Symbol: SREBF1
SREBF1
CUI: C0011847
Disease:
Diabetes 		0.020 GeneticVariation BEFREE Also, three other SNPs (rs2236513, rs6502618 and rs1889018), located in the 5' region, were significantly associated with diabetes risk (OR > or =1.21, p< or =0.006). 17019602 2006
dbSNP: rs11868035
rs11868035
Entrez Id: 6720;10743
Gene Symbol: SREBF1;RAI1
SREBF1;RAI1
CUI: C0011847
Disease:
Diabetes 		0.010 GeneticVariation BEFREE In the case-control studies, carriers of the minor allele of the previously reported SNP (rs11868035) had a significantly increased diabetes risk (odds ratio [OR]=1.20 [95% CI 1.04-1.38], p=0.015). 17019602 2006