AURKA, aurora kinase A, 6790

N. diseases: 245; N. variants: 15
Disease: Stomach Carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1047972
rs1047972
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
CUI: C0699791
Disease:
Stomach Carcinoma 		0.030 GeneticVariation BEFREE Our results revealed that AURKA (rs1047972 and rs911160), AURKB (rs2241909 and rs2289590) and AURKC (rs11084490) are associated with a higher risk of GC susceptibility. 31521144 2019
dbSNP: rs1047972
rs1047972
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
CUI: C0699791
Disease:
Stomach Carcinoma 		0.030 GeneticVariation BEFREE Based on these results, we can conclude that AURKA rs1047972 and AURKC rs758099 polymorphisms could affect the risk of GC development. 27270838 2016
dbSNP: rs1047972
rs1047972
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
CUI: C0699791
Disease:
Stomach Carcinoma 		0.030 GeneticVariation BEFREE The results suggest that 169G>A in AURKA is associated with progression of gastric cancer by affecting relative kinase activities of AURKA variants. 16412566 2006
dbSNP: rs911160
rs911160
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
CUI: C0699791
Disease:
Stomach Carcinoma 		0.020 GeneticVariation BEFREE Our results revealed that AURKA (rs1047972 and rs911160), AURKB (rs2241909 and rs2289590) and AURKC (rs11084490) are associated with a higher risk of GC susceptibility. 31521144 2019
dbSNP: rs2273535
rs2273535
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
CUI: C0699791
Disease:
Stomach Carcinoma 		0.020 GeneticVariation BEFREE In addition, TT genotypes of rs2273535 polymorphism increased the risk of GC by 72% compared to the AA genotypes. 30174615 2018
dbSNP: rs911160
rs911160
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
CUI: C0699791
Disease:
Stomach Carcinoma 		0.020 GeneticVariation BEFREE Our findings suggested that AURKA (rs911160) and AURKB (rs2289590) polymorphisms could affect GC risk. 28843004 2017
dbSNP: rs2273535
rs2273535
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
CUI: C0699791
Disease:
Stomach Carcinoma 		0.020 GeneticVariation BEFREE We genotyped four SNPs in AURKA (rs2273535 and rs1047972), AURKB (rs2241909), and AURKC (rs758099) in a total of 128 GC patients and 372 healthy controls using TaqMan allelic discrimination assays to evaluate their effects on GC risk. 27270838 2016