TCF4, transcription factor 4, 6925

N. diseases: 378; N. variants: 111
Disease: Primary sclerosing cholangitis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1452787
rs1452787
Entrez Id: 6925
Gene Symbol: TCF4
TCF4
CUI: C0566602
Disease:
Primary sclerosing cholangitis 		0.010 GeneticVariation BEFREE We discovered novel genome-wide significant associations with PSC at 2q37 [rs3749171 at G-protein-coupled receptor 35 (GPR35); P = 3.0 × 10(-9) in the overall study population, combined odds ratio [OR] and 95% confidence interval [CI] of 1.39 (1.24-1.55)] and at 18q21 [rs1452787 at transcription factor 4 (TCF4); P = 2.61 × 10(-8) , OR (95% CI) = 0.75 (0.68-0.83)]. 22821403 2013