TLR2, toll like receptor 2, 7097

N. diseases: 749; N. variants: 15
Disease: Septicemia ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5743708
rs5743708
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0036690
Disease:
Septicemia 		0.030 GeneticVariation BEFREE The TLR2 Arg753Gln polymorphism might be used as a relevant risk estimate for the development of sepsis. 26616674 2015
dbSNP: rs5743708
rs5743708
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0036690
Disease:
Septicemia 		0.030 GeneticVariation BEFREE We investigated the supposed-2029C>T and 2258G>A TLR2 polymorphisms in 422 critically ill patients of European origin from southern Brazil (295 with sepsis and 127 without sepsis) and reviewed 33 studies on these polymorphisms, conducting a quality assessment with a score system. 20578945 2010
dbSNP: rs5743708
rs5743708
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0036690
Disease:
Septicemia 		0.030 GeneticVariation BEFREE Single nucleotide polymorphisms (SNPs) Arg753Gln and Arg677Trp affect TLR2 responsiveness and may contribute to the course of sepsis, which is associated with substantial morbidity and mortality during intensive care treatment. 18249133 2008
dbSNP: rs3804099
rs3804099
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0036690
Disease:
Septicemia 		0.020 GeneticVariation BEFREE The rs3804099 and the haplotype ATT might be used as relevant risk estimates for the development of sepsis and MOD in patients with major trauma. 20577149 2011
dbSNP: rs3804099
rs3804099
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0036690
Disease:
Septicemia 		0.020 GeneticVariation BEFREE Polymorphisms in TLR2 (rs3804099), TLR5 (rs5744105), IL10 (rs1800896), and PLA2G2A (rs1891320) genes were associated with sepsis. 20463618 2010
dbSNP: rs121917864
rs121917864
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0036690
Disease:
Septicemia 		0.010 GeneticVariation BEFREE Single nucleotide polymorphisms (SNPs) Arg753Gln and Arg677Trp affect TLR2 responsiveness and may contribute to the course of sepsis, which is associated with substantial morbidity and mortality during intensive care treatment. 18249133 2008