VWF, von Willebrand factor, 7450

N. diseases: 498; N. variants: 158
Disease: Coronary heart disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs216311
rs216311
Entrez Id: 7450
Gene Symbol: VWF
VWF
CUI: C0010068
Disease:
Coronary heart disease 		0.010 GeneticVariation BEFREE In summary, vWF gene polymorphisms at site A1381T were not associated with coronary heart disease, but plasma vWF levels were influenced by vWF gene polymorphisms at site A1381T, blood type and coronary heart disease. 22923007 2012
dbSNP: rs1063856
rs1063856
Entrez Id: 7450
Gene Symbol: VWF
VWF
CUI: C0010068
Disease:
Coronary heart disease 		0.010 GeneticVariation BEFREE In conclusion, although the Thr789Ala vWF gene variant is associated with increased plasma concentrations of vWF, ristocetin co factor levels and collagen binding capacity in patients with type 2 diabetes and CHD, a direct effect of this variant on the occurrence of CHD in patients with type 2 diabetes, could not be detected. 16320153 2005