XBP1, X-box binding protein 1, 7494

N. diseases: 234; N. variants: 6
Disease: Crohn Disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs35873774
rs35873774
Entrez Id: 7494
Gene Symbol: XBP1
XBP1
CUI: C0010346
Disease:
Crohn Disease 		0.010 GeneticVariation BEFREE An association of XBP1 variants with both forms of human IBD (Crohn's disease and ulcerative colitis) was identified and replicated (rs35873774; p value 1.6 x 10(-5)) with novel, private hypomorphic variants identified as susceptibility factors. 18775308 2008