DisGeNET - a database of gene-disease associations

EVI5, ecotropic viral integration site 5, 7813

N. diseases: 22; N. variants: 16

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs11810217

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C0026769
Disease:

Multiple Sclerosis

0.810

GeneticVariation

BEFREE

In addition, T G T haplotype (rs6680578, rs10735781 and rs11810217 respectively) was associated with MS risk while T C C, A G T and A C T had a protective effect against MS.

29141798

2017

dbSNP:

rs11810217

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C0026769
Disease:

Multiple Sclerosis

0.810

GeneticVariation

GWASCAT

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

21833088

2011

dbSNP:

rs11810217

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C0026769
Disease:

Multiple Sclerosis

0.810

GeneticVariation

GWASDB

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

21833088

2011

dbSNP:

rs7515577

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C1445957
Disease:

Serum total cholesterol measurement

0.800

GeneticVariation

GWASCAT

A large electronic-health-record-based genome-wide study of serum lipids.

29507422

2018

dbSNP:

rs7515577

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C1445957
Disease:

Serum total cholesterol measurement

0.800

GeneticVariation

GWASCAT

Discovery and refinement of loci associated with lipid levels.

24097068

2013

dbSNP:

rs7515577

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C1445957
Disease:

Serum total cholesterol measurement

0.800

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

dbSNP:

rs7515577

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C1445957
Disease:

Serum total cholesterol measurement

0.800

GeneticVariation

GWASDB

Biological, clinical and population relevance of 95 loci for blood lipids.

20686565

2010

dbSNP:

rs7515577

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C1445957
Disease:

Serum total cholesterol measurement

0.800

GeneticVariation

GWASCAT

Biological, clinical and population relevance of 95 loci for blood lipids.

20686565

2010

dbSNP:

rs10735781

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C0026769
Disease:

Multiple Sclerosis

0.710

GeneticVariation

BEFREE

In addition, T G T haplotype (rs6680578, rs10735781 and rs11810217 respectively) was associated with MS risk while T C C, A G T and A C T had a protective effect against MS.

29141798

2017

dbSNP:

rs11808092

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C0026769
Disease:

Multiple Sclerosis

0.710

GeneticVariation

GWASCAT

Genetic loci for Epstein-Barr virus nuclear antigen-1 are associated with risk of multiple sclerosis.

26819262

2016

dbSNP:

rs10735781

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C0026769
Disease:

Multiple Sclerosis

0.710

GeneticVariation

GWASDB

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

21833088

2011

dbSNP:

rs11808092

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C0026769
Disease:

Multiple Sclerosis

0.710

GeneticVariation

BEFREE

We observed an association with MS in three of eight Tag-SNPs: rs11804321 (P=0.008, OR=1.29; 95% CI=1.08-1.54), rs11808092 (P=0.048, OR=1.19; 95% CI=1.03-1.39) and rs6680578 (P=0.0082, OR=1.23; 95% CI=1.07-1.41).

20087403

2010

dbSNP:

rs34231012

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C0013595
Disease:

Eczema

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs6422513

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C1305855
Disease:

Body mass index

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs6422513

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C0005890
Disease:

Body Height

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs6604015

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C1305855
Disease:

Body mass index

0.700

GeneticVariation

GWASCAT

Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.

30239722

2019

dbSNP:

rs12743520

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C1527304
Disease:

Allergic Reaction

0.700

GeneticVariation

GWASCAT

A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

29785011

2018

dbSNP:

rs12743520

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C0004096
Disease:

Asthma

0.700

GeneticVariation

GWASCAT

A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

29785011

2018

dbSNP:

rs145955280

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C1445957
Disease:

Serum total cholesterol measurement

0.700

GeneticVariation

GWASCAT

Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.

30275531

2018

dbSNP:

rs145955280

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C0202117
Disease:

Low density lipoprotein cholesterol measurement

0.700

GeneticVariation

GWASCAT

Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.

30275531

2018

dbSNP:

rs2027061

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C1445957
Disease:

Serum total cholesterol measurement

0.700

GeneticVariation

GWASCAT

A large electronic-health-record-based genome-wide study of serum lipids.

29507422

2018

dbSNP:

rs2027061

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C0202117
Disease:

Low density lipoprotein cholesterol measurement

0.700

GeneticVariation

GWASCAT

A large electronic-health-record-based genome-wide study of serum lipids.

29507422

2018

dbSNP:

rs7515577

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C0202117
Disease:

Low density lipoprotein cholesterol measurement

0.700

GeneticVariation

GWASCAT

A large electronic-health-record-based genome-wide study of serum lipids.

29507422

2018

dbSNP:

rs11578098

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C0024141
Disease:

Lupus Erythematosus, Systemic

0.700

GeneticVariation

GWASCAT

Transancestral mapping and genetic load in systemic lupus erythematosus.

28714469

2017

dbSNP:

rs6603981

Entrez Id:	7813
Gene Symbol:	EVI5

EVI5

CUI:	C1445957
Disease:

Serum total cholesterol measurement

0.700

GeneticVariation

GWASCAT

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.

28334899

2017