DPF3, double PHD fingers 3, 8110

N. diseases: 20; N. variants: 9
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4903064
rs4903064
Entrez Id: 8110
Gene Symbol: DPF3
DPF3
CUI: C0007134
Disease:
Renal Cell Carcinoma 		C 0.710 GeneticVariation GWASCAT Sex specific associations in genome wide association analysis of renal cell carcinoma. 31231134 2019
dbSNP: rs4903064
rs4903064
Entrez Id: 8110
Gene Symbol: DPF3
DPF3
CUI: C0007134
Disease:
Renal Cell Carcinoma 		C 0.710 GeneticVariation GWASCAT We confirm the six known RCC risk loci and identify seven new loci at 1p32.3 (rs4381241, P=3.1 × 10<sup>-10</sup>), 3p22.1 (rs67311347, P=2.5 × 10<sup>-8</sup>), 3q26.2 (rs10936602, P=8.8 × 10<sup>-9</sup>), 8p21.3 (rs2241261, P=5.8 × 10<sup>-9</sup>), 10q24.33-q25.1 (rs11813268, P=3.9 × 10<sup>-8</sup>), 11q22.3 (rs74911261, P=2.1 × 10<sup>-10</sup>) and 14q24.2 (rs4903064, P=2.2 × 10<sup>-24</sup>). 28598434 2017
dbSNP: rs4903064
rs4903064
Entrez Id: 8110
Gene Symbol: DPF3
DPF3
CUI: C0007134
Disease:
Renal Cell Carcinoma 		0.710 GeneticVariation BEFREE We confirm the six known RCC risk loci and identify seven new loci at 1p32.3 (rs4381241, P=3.1 × 10<sup>-10</sup>), 3p22.1 (rs67311347, P=2.5 × 10<sup>-8</sup>), 3q26.2 (rs10936602, P=8.8 × 10<sup>-9</sup>), 8p21.3 (rs2241261, P=5.8 × 10<sup>-9</sup>), 10q24.33-q25.1 (rs11813268, P=3.9 × 10<sup>-8</sup>), 11q22.3 (rs74911261, P=2.1 × 10<sup>-10</sup>) and 14q24.2 (rs4903064, P=2.2 × 10<sup>-24</sup>). 28598434 2017
dbSNP: rs202075571
rs202075571
Entrez Id: 8110
Gene Symbol: DPF3
DPF3
CUI: C0427460
Disease:
Red cell distribution width determination 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs202075571
rs202075571
Entrez Id: 8110
Gene Symbol: DPF3
DPF3
CUI: C1304746
Disease:
RDW - Red blood cell distribution width result 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs61986330
rs61986330
Entrez Id: 8110
Gene Symbol: DPF3
DPF3
CUI: C1305855
Disease:
Body mass index 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs6574100
rs6574100
Entrez Id: 8110
Gene Symbol: DPF3
DPF3
CUI: C1305855
Disease:
Body mass index 		A 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs10140566
rs10140566
Entrez Id: 8110
Gene Symbol: DPF3
DPF3
CUI: C0040420
Disease:
Tonometry 		T 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify new loci influencing intraocular pressure. 29617998 2018
dbSNP: rs12887388
rs12887388
Entrez Id: 8110
Gene Symbol: DPF3
DPF3
CUI: C0242383
Disease:
Age related macular degeneration 		G 0.700 GeneticVariation GWASCAT Genome-wide analysis of disease progression in age-related macular degeneration. 29346644 2018
dbSNP: rs7160830
rs7160830
Entrez Id: 8110
Gene Symbol: DPF3
DPF3
CUI: C0410702
Disease:
Adolescent idiopathic scoliosis 		0.700 GeneticVariation GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018
dbSNP: rs7160830
rs7160830
Entrez Id: 8110
Gene Symbol: DPF3
DPF3
CUI: C1837461
Disease:
SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 		0.700 GeneticVariation GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018
dbSNP: rs74884082
rs74884082
Entrez Id: 8110
Gene Symbol: DPF3
DPF3
CUI: C0004238
Disease:
Atrial Fibrillation 		C 0.700 GeneticVariation GWASCAT Biobank-driven genomic discovery yields new insight into atrial fibrillation biology. 30061737 2018
dbSNP: rs74884082
rs74884082
Entrez Id: 8110
Gene Symbol: DPF3
DPF3
CUI: C0004238
Disease:
Atrial Fibrillation 		C 0.700 GeneticVariation GWASCAT Multi-ethnic genome-wide association study for atrial fibrillation. 29892015 2018
dbSNP: rs10129954
rs10129954
Entrez Id: 8110
Gene Symbol: DPF3
DPF3
CUI: C0021364
Disease:
Male infertility 		0.020 GeneticVariation BEFREE A total of 136 subfertile men and 456 healthy fertile men were recruited. rs6476866 in SLC1A1 (P = 1.919E-4, OR = 0.5905, 95% CI: 0.447-0.78) and rs10129954 in DPF3 (P = 0.0023, OR = 2.199, 95% CI: 1.311-3.689) were strongly associated with idiopathic male infertility. 27232852 2018
dbSNP: rs10129954
rs10129954
Entrez Id: 8110
Gene Symbol: DPF3
DPF3
CUI: C0021364
Disease:
Male infertility 		0.020 GeneticVariation BEFREE In this study, we investigated whether the rs10966811 (located in an intergenic region between the TUSC1 and IZUMO3 genes) and rs10129954 (located in the DPF3 gene) SNPs, previously related to family size, are associated with male infertility. 28975488 2018
dbSNP: rs10129954
rs10129954
Entrez Id: 8110
Gene Symbol: DPF3
DPF3
CUI: C0004509
Disease:
Azoospermia 		0.010 GeneticVariation BEFREE Also, a statistically significant association between rs10129954 and azoospermia, and oligozoospermia was observed. 28975488 2018
dbSNP: rs4903064
rs4903064
Entrez Id: 8110
Gene Symbol: DPF3
DPF3
CUI: C0279702
Disease:
Conventional (Clear Cell) Renal Cell Carcinoma 		0.010 GeneticVariation BEFREE We confirm the six known RCC risk loci and identify seven new loci at 1p32.3 (rs4381241, P=3.1 × 10<sup>-10</sup>), 3p22.1 (rs67311347, P=2.5 × 10<sup>-8</sup>), 3q26.2 (rs10936602, P=8.8 × 10<sup>-9</sup>), 8p21.3 (rs2241261, P=5.8 × 10<sup>-9</sup>), 10q24.33-q25.1 (rs11813268, P=3.9 × 10<sup>-8</sup>), 11q22.3 (rs74911261, P=2.1 × 10<sup>-10</sup>) and 14q24.2 (rs4903064, P=2.2 × 10<sup>-24</sup>). 28598434 2017