SOAT2, sterol O-acyltransferase 2, 8435

N. diseases: 25; N. variants: 2
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs28765985
rs28765985
Entrez Id: 8435
Gene Symbol: SOAT2
SOAT2
CUI: C1956346
Disease:
Coronary Artery Disease 		0.010 GeneticVariation BEFREE Subjects with CC/CT genotype or C allele of rs28765985 were associated with an increased risk of CAD. 30696703 2019
dbSNP: rs9658625
rs9658625
Entrez Id: 8435
Gene Symbol: SOAT2
SOAT2
CUI: C1561643
Disease:
Chronic Kidney Diseases 		0.010 GeneticVariation BEFREE Subsequent multivariable logistic regression analysis with adjustment for covariates as well as a stepwise forward selection procedure revealed that the T --> C (Val591Ala) polymorphism of APOB (rs679899), the -681C --> G polymorphism of PPARG (rs10865710), the T --> C (Cys1367Arg) polymorphism of WRN (rs1346044), the -850C --> T polymorphism of TNF (rs1799724), the -219G --> T polymorphism of APOE (rs405509), the C --> T polymorphism of PTGS1 (rs883484) and the 41A --> G (Glu14Gly) polymorphism of ACAT2 (rs9658625) were significantly (P<0.05) associated with the prevalence of CKD. 19282863 2009